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Drug Hypersensitivity: How Drugs Stimulate T Cells via Pharmacological Interaction with Immune Receptors

Creator:

Pichler, Werner J., Adam, Jacqueline, Watkins, Stephen, Wuillemin, Natascha, Yun, James, and Yerly, Daniel

Abstract:

Small chemicals like drugs tend to bind to proteins via noncovalent bonds, e.g. hydrogen bonds, salt bridges or electrostatic interactions. Some chemicals interact with other molecules than the actual target ligand, representing so-called ‘off-target' activities of drugs. Such interactions are a main cause of adverse side effects to drugs and...

Resource Type:

Article

Full Text:

depends on the frequency of the involved allele in a given population. Carbamazepine-induced Stevens
1996/1997 Annual Report

Creator:

Hatfield Marine Science Center

Abstract:

Report year ends June 30.

Resource Type:

Other

Full Text:

ANNUAL REPORT 1996-97 Steven Berkeley: Marine Fisheries During 1996-97, Steve Berkeley continued his