Index Catalog // ScholarsArchive@OSU

Characterization and Validation of Neisseria gonorrhoeae Proteins GmhAGC and NGO1985 as Molecular Targets for Development of Novel Anti-gonorrhea Therapeutic Interventions

Creator:: Wierzbicki, Igor H.
Abstract:: The sexually transmitted disease gonorrhea, caused by the Gram-negative bacterium and obligate human pathogen Neisseria gonorrhoeae, remains a significant health and economic burden worldwide. In the absence of a protective vaccine, antimicrobial agents are the only pharmacological intervention for patients with gonorrhea. However, due to the remarkable ability of gonococcus...
Resource Type:: Dissertation
Full Text:: . ©Copyright by Igor H. Wierzbicki September 28, 2016 All Rights Reserved Characterization and

Automated analysis, design, and optimization of low noise oscillators

Creator:: Vytyaz, Igor
Abstract:: Low noise oscillators are universally needed in digital systems for clock generation and synchronization, and in radio-frequency communication front-ends for frequency up- and down-conversion. Noise in oscillators results in timing jitter, and limits the clock frequency of digital systems. In radio-frequency communication systems, phase noise in oscillators lowers the signal-to-noise...
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE DISSERTATION OF Igor Vytyaz for the degree of

Logical implications between different flavors of asphericity

Creator:: Biskup, Igor Marko
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE DISSERTATION OF Igor M. Biskup for the

Comparison of time-domain and frequency-domain phase noise analyses

Creator:: Vytyaz, Igor
Abstract:: This thesis presents a comparison of time-domain and frequency-domain algorithms for phase noise calculation in oscillators. Floquet theory provides the mathematical foundation for these calculations and the numerical methods employ perturbation projection vectors (PPVs). The PPVs are an estimate of an oscillator's sensitivity to noise. The in-house circuit simulator SPICE3...
Resource Type:: Masters Thesis
Full Text:: AN ABSTRACT OF THE THESIS OF Igor Vytyaz for the degree of Master of

The role of the vertebral column during jumping in quadrupedal mammals

Creator:: Harty, Tyson H.
Abstract:: Little, if any, quantifications have been made on the contribution of the vertebral column during jumping in quadrupedal mammals. Previous studies of jumpers have focused on the morphological and physiological specializations of the hindlimbs. In this study, such specialization was measured during the supramaximal jumps of the Pacific jumping mouse...
Resource Type:: Dissertation
Full Text:: DISSERTATION OF Tyson H. Harty for the degree of Doctor of Philosophy in Zoology presented on March 2, 2010

Reaction Pathways of Oxo-Hydroxo Group 5 Clusters to Metal Oxide Thin Films

Creator:: Mansergh, Ryan H.
Abstract:: Oxo-hydroxo Group 5 metal clusters are an untapped resource to study and advance aqueous solution processing of metal oxide thin films. The tetramethylammonium (TMA) hexatantalate salt (TMA6[H2Ta6O19]) yields dense Ta2O5 films (~95% of the bulk ß-Ta2O5 density) with atomically smooth surfaces (<4 Å root mean square surface roughness). This same...
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE DISSERTATION OF Ryan H. Mansergh

Cloning and biochemical characterization of the hectochlorin biosynthetic gene cluster from the marine cyanobacterium Lyngbya majuscula

Creator:: Ramaswamy, Aishwarya V.
Abstract:: Cyanobacteria are rich in biologically active secondary metabolites, many of which have potential application as anticancer or antimicrobial drugs or as useful probes in cell biology studies. A Jamaican isolate of the marine cyanobacterium, Lyngbya majuscula was the source of a novel antifungal and cytotoxic secondary metabolite, hectochlorin. The structure...
Resource Type:: Dissertation
Full Text:: Lyngbya maluscula Abstract approved: William H. Gerwick Cyanobacteria are rich in biologically active

Applications of Holographic Optical Tweezers: Multiplexed Fluorescence Spectroscopy and the Micromechanics of Type-I Collagen

Creator:: Cibula, Matthew A.
Abstract:: The development and some applications of holographic optical tweezers (HOT) are presented. Our HOT system uses a spatial light modulator (SLM) to control the location and properties of the optical trap. We have developed a method for optimizing the diffraction efficiency of a SLM that can be applied in situ...
Resource Type:: Dissertation
Full Text:: Type-I Collagen Abstract approved: David H. McIntyre The development and some applications of

Overexpression of antioxidant genes in transgenic tomato tolerant against multiple stresses

Creator:: Wang, Yueju
Abstract:: The effect of increased manganese superoxide dismutase (Mn-SOD) and cytosolic ascorbate peroxidase (cAPX) on various abiotic stresses was studied using transgenic tomato (Lycopersicon esculentum) plants. Transformants were selected in vitro based on kanamycin resistance, confirmed by PCR and northern blot analyses. Northern blots showed an enhanced gene expression of Mn-SOD...
Resource Type:: Dissertation
Full Text:: Leslie H. Fuchigami £/ The effect of increased manganese superoxide dismutase (Mn-SOD) and cytosolic

Origins and evolution of plant microRNA genes

Creator:: Fahlgren, Noah
Abstract:: Eukaryotic small RNA (~20-30 nucleotides) are diverse regulatory molecules that repress gene expression at the transcriptional and post-transcriptional levels, defend hosts against invading viruses and defend genomes against selfish DNA elements. Small RNA populations are studied by high-throughput sequencing of the total small RNA fraction isolated from cells, however, the...
Resource Type:: Dissertation
Full Text:: , Scott A. Givan and Tyler W. H. Backman wrote and tested the CASHX alignment algorithm and the CASHX

ScholarsArchive@OSU

Characterization and Validation of Neisseria gonorrhoeae Proteins GmhAGC and NGO1985 as Molecular Targets for Development of Novel Anti-gonorrhea Therapeutic Interventions

Automated analysis, design, and optimization of low noise oscillators

Logical implications between different flavors of asphericity

Comparison of time-domain and frequency-domain phase noise analyses

The role of the vertebral column during jumping in quadrupedal mammals

Reaction Pathways of Oxo-Hydroxo Group 5 Clusters to Metal Oxide Thin Films

Cloning and biochemical characterization of the hectochlorin biosynthetic gene cluster from the marine cyanobacterium Lyngbya majuscula

Applications of Holographic Optical Tweezers: Multiplexed Fluorescence Spectroscopy and the Micromechanics of Type-I Collagen

Overexpression of antioxidant genes in transgenic tomato tolerant against multiple stresses

Origins and evolution of plant microRNA genes

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