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Creator:: Starman, Alia
Abstract:: Multicellular coordination in response to environmental stimuli is essential in biology, and this coordination is often achieved by a division of labor to establish leaders and followers in a cell population. This is called emergent leadership, but how a cell adopts its role and effectively exchanges information with peers is...
Resource Type:: Honors College Thesis
Full Text:: approved:_____________________________________________________ Patrick Chappell Multicellular

Creator:: Ewton, Jessica
Abstract:: Gonadotropin-releasing hormone (GnRH) neurons are able to trigger the release of luteinizing hormone and follicle-stimulating hormone which control the maturation of oocytes and ovulation which is vital for reproduction. They are the most downstream neurons that project to the median eminence into the pituitary portal where they release GnRH. Modulation...
Resource Type:: Honors College Thesis
Full Text:: Hormone Expressing Neurons. Abstract approved: a Patrick Chappell Gonadotropin-releasing hormone (GnRH

Creator:: Rogers, Zackry L.
Abstract:: Breast cancer is a leading cause of cancer deaths among women, with an estimated 12.4% of American women diagnosed with this tumor type. Evidence suggests that exogenous disruptors can exert epigenetic changes leading to aberrant gene expression, shifting the cellular balance toward oncogenesis. While chemical pollutant exposure is well-studied, light...
Resource Type:: Honors College Thesis
Full Text:: Mammary Gland. Abstract approved:_____________________________________________________ Patrick Chappell

Creator:: Rayzman, Noa
Abstract:: Estradiol (E2) plays a role in positive and negative feedback mechanisms of the hypothalamic-pituitary-gonadal (HPG) axis in female mammals. These mechanisms are regulated by two different populations of kisspeptin (KP)-producing neurons: anteroventral periventricular (AVPV) neurons, which are stimulated by E2, and arcuate (arc) neurons, which are inhibited by E2. AVPV...
Resource Type:: Honors College Thesis
Full Text:: approved:_____________________________________________________ Patrick Chappell Estradiol (E2) plays a

Creator:: James, Teagan
Abstract:: Estrogen (E2) is essential for multiple physiological effects in females, ensuring maximum reproductive fitness and maintaining skeletal homeostasis. E2 has been shown to stimulate cancellous bone formation via activation of estrogen receptor alpha (ERα), an effect widely accepted to be mediated directly at bone. A recent landmark study by Herber...
Resource Type:: Honors College Thesis
Full Text:: :_____________________________________________________ Patrick Chappell Estrogen (E2) is essential for multiple physiological effects in females

Creator:: Aponso, Hiruni M.
Abstract:: Breast cancer is the second most common cancer among women in the US, however, only a small fraction of cases are attributable to heritable genetic mutations; the bulk arises from various behavioral and environmental factors. Loss of functional p53 is observed in over 50% of cases, and its activity relies...
Resource Type:: Honors College Thesis
Full Text:: :_____________________________________________________ Patrick Chappell Breast cancer is the second most common cancer among women in the US

Creator:: Grimwood, Victoria J.
Abstract:: Endogenous circadian clock regulation is essential to normal rhythmicity, particularly the timing of hormone release in the brain. In the context of mammalian reproduction, a surge of a specific hormone, gonadotrophin-releasing hormone (GnRH), initiates a surge of luteinizing hormone (LH) from the pituitary gland, which is required for ovulation in...
Resource Type:: Honors College Thesis

Creator:: Ferguson, Lindsey G.
Abstract:: Aquatic animals possess surprising similarities to humans in reproductive signaling that are simplified or elaborated for life underwater, making them useful for studying reproductive control. In this thesis, killifish and sea anemones are used as models for reproductive function and aging. The aging model Nothobranchius (killifish) was used to investigate...
Resource Type:: Honors College Thesis
Full Text:: Patrick Chappell Aquatic animals possess surprising similarities to humans in reproductive signaling

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