Index Catalog // ScholarsArchive@OSU

Creator:: Kapsi, Shivakumar G.
Abstract:: This thesis describes 1) development of a gastric retention device (GRD) to increase gastric retention time of certain drugs, 2) product formulations of an immediate release itraconazole and controlled-release ketoprofen. GRD was fabricated from crosslinked carbohydrate polymers. Rate and extent of hydration of the film in water and in simulated...
Resource Type:: Dissertation
Full Text:: every formulation and delivery system developed is intended to deliver a particular drug in a

Creator:: Ahmed, Iman Saad
Abstract:: This thesis describes evaluation of a gastric retention device (GRD) developed at Oregon State University. The device was originally fabricated from Xanthan gum and Locust bean gum. A modified gastric retention device containing other additives was developed and investigated in this work. The modified device was evaluated in vitro for...
Resource Type:: Dissertation
Full Text:: a New Colonic Delivery System. INTRODUCTION Site-specific drug targeting to different regions in

Creator:: Dill, Justen K.
Abstract:: A more quantitative understanding of peptide loading and release from polyethylene oxide (PEO) brush layers will provide direction for development of new strategies for drug storage and delivery. The antimicrobial peptide nisin shows potent activity against Gram-positive bacteria including the most prevalent implant-associated pathogens, its mechanism of action minimizes the...
Resource Type:: Masters Thesis
Full Text:: possible drug storage, delivery, and biocompatibility may be explored. 4 Literature Review

Creator:: Pham, Loan
Abstract:: The thrust of this thesis is to study oral solid dosage formulation using hot melt coating method and to use pharmacokinetic modeling and simulation (PK M&S) as a tool that can help to predict pharmacokinetics of a drug in human and the probability of passing various bioequivalence criteria of the...
Resource Type:: Dissertation
Full Text:: offer another choice to produce IR and SR drug delivery formulations using single and double coating

Creator:: Rakkanka, Vipaporn
Abstract:: This thesis describes evaluation of a novel self-sealing chewable sustained release tablet that can maintain controlled release of drug regardless of compaction, crushing, or chewing. The new formulation contains polyethylene oxide which produces a sealant effect for cracks produced in the polymer coating during compaction. Dissolution studies were conducted and...
Resource Type:: Dissertation
Full Text:: Formulations, (3) A Novel Zero Order Release Matrix Tablet. INTRODUCTION The oral route of drug delivery is

Creator:: Doddapaneni, Bhuvana S.
Abstract:: Poor aqueous solubility of a large number of newly discovered chemical entities is posing a significant challenge for the formulation industry and is delaying their drug development. The number of formulation techniques available to solubilize these poorly soluble molecules is very limited. In addition to that, traditional formulation methods involve...
Resource Type:: Dissertation
Full Text:: ..................................................................................................................... 17 A three-drug nanoscale drug delivery system designed for preferential lymphatic uptake for the

Creator:: Tantituvanont, Angkana
Abstract:: This dissertation describes two different projects. The first is the development of an oral DNA vaccine delivery system for fish. A novel oral DNA vaccine delivery system was developed for Rainbow Trout by combining non-viral vectors (polycationic liposomes or polycationic polymer) to facilitate the DNA vaccine's uptake by cell membranes...
Resource Type:: Dissertation
Full Text:: : Development of Oral Microparticulate Non-Viral DNA Vaccine Delivery System against Infectious Hematopoetic

Creator:: Sartnurak, Soisurin
Abstract:: The stability of valproate sodium syrup repackaged in three types of unit dose containers was studied. Two-milliliter samples of commercial valproate sodium syrup 250 mg/5 ml (of valproic acid) were packaged in polypropylene oral syringes, glass oral syringes, and glass vials (126 of each type). These were stored at 4,...
Resource Type:: Masters Thesis
Full Text:: lower tempera- tures. An average of 86% of the drug lost from the polypropylene syringes was recovered

Creator:: Matthews, David J.
Abstract:: Flexible electronics processing techniques were applied to integrate a glucose sensor with a hormone-delivery catheter in order to create a cheap and minimally invasive method for patients with type 1 diabetes to continually monitor and control their blood sugar levels. Ultimately, this work intends to move toward the development of...
Resource Type:: Masters Thesis
Full Text:: glucose sensor with a hormone-delivery catheter in order to create a cheap and minimally invasive

ScholarsArchive@OSU