The induction of drug-metabolizing enzymes is a
complex biochemical process manifested not only by
increases in various cytochrome P-450 isozymes and
related activities, but also by alterations in
endoplasmic reticulum membranes. Little work has been
done to examine how cytochrome P-450 inducing agents
influence other cellular processes, such as
phospholipid...
Five species of aquatic organisms were exposed to TCDD. Lethal effects of initial exposure to coho salmon of 23.4 nanogram TCDD/gram fish wet weight (23.4 ng/g), or equivalent to 100 nanogram
per liter (100 ng/l) TCDD in water, for 24 hours were irreversible; 95% mortality occurred in 60 days. Exposure...
In the first experiment the minimum dietary toxic levels of vitamin A were determined in pregnant rabbits over three parities. The treatments consisted of basal diet plus 10,000, 30,000, 60,000, and 90,000 IU/Kg added vitamin A. The basal diet was formulated to be free of vitamin A and beta-carotene; rice...
Recent research conducted throughout the Northern California Current (NCC) on the ecology of Pacific salmon (Oncorhynchus spp.) indicates that variable ocean conditions affect the community composition of zooplankton in the nearshore environment which, in turn, can affect the quality of prey for fish, sea birds and mammals. Interannual variability in...
Understanding the effects of climate variability on growth dynamics and timing of early life history events in marine fishes can provide insights into survival, recruitment and productivity. Field collections (2005, 2007, 2009-2011) were combined with otolith microstructural analysis to examine interannual variation in larval and juvenile growth rates, size at...
Miller Lake was chemically treated with toxaphene on September 16, 1958 to destroy a population of parasitic lamprey (E.tridentatus) and Tui Chub (Siphatelep bicolor). Toxaphene was applied at the rate of 0.04 ppm. No lamprey or fish have been collected in the lake since the chemical treatment. Work since 1959...