Circadian clocks are internal mechanisms regulating many physiological processes.
Research suggests that the circadian clock may regulate repair of cellular damage caused
by reactive oxygen species (ROS), but molecular pathways from the clock to ROS repair
are not known. The gene cncC, known in mammals as Nrf2, and its repressor...
Paper microfluidic devices are capable of processing fluids using capillary flow in materials that are lower cost than the standard materials used in microfluidics. Due to the low cost of their fabrication and minimal requirements for instrumentation, paper microfluidic devices are ideal for use in low-resource settings. They have the...
Osmotic stress is a common challenge faced by organisms in environments with variable salinity or aridity. Understanding the evolutionary mechanisms underlying adaptation to osmotic stress may have wide applications, including management of populations experiencing climate change, or engineering industrial organisms involved in processes such as fermentation. While Saccharomyces cerevisiae is...
Despite the recognized role of soil arthropod fauna on nutrient cycling
and decomposition processes, many aspects of the effects of sylvicultural
methods in forest ecosystems upon their biology remain poorly understood.
The long term effects of prescribed fires on soil arthropods in forest
ecosystems in the Pacific Northwest have never...
Defensive chemical and nutritive quality of young leaves were measured for 72 individual trees of Chrysolepis [Castanopsis] chrysophylla in conjunction with light intensities of two different stand types and population numbers of Habrodais grunus herri in the Cascade mountains of Oregon. Leaves were collected in the spring and leaf characteristics...
Skeletal muscle is the largest organ in the body by mass, comprising roughly 40% of total bodyweight in adults. It plays diverse and unique roles that include movement, locomotion, and support for posture and internal organs, among others. The structural foundation for all skeletal muscle in adults is formed early...
This research investigated gene expression in the canine placenta during the peripartum period. Previous studies have recognized molecular changes that occur in the placenta around the time of placental release in other species, but no study has looked at gene expression in the late gestation canine placenta. Of particular significance...
Sialic acids are involved in many cellular interactions. They can serve as an adhesion ligand or act as an inhibitor to cellular adhesion by charge repulsion or by masking potential ligands. Although sialic acids are implicated in the process of blastocyst implantation, their expression and regulation in uterine epithelium of...
The spatial and temporal patterning of sequence specific transcription factors (SSTFs) contributes to cell type specification and organ formation during embryogenesis. Homeodomain transcription factors are evolutionally conserved among invertebrate and vertebrate animals. They are responsible for body segmentation and organogenesis. Lbx1 and Pitx2 both are homeodomain transcription factors contributing to...
This research investigated the development of a novel canine model to study preeclampsia. Normal canine placental development has morphologic and histologic similarities to the shallow trophoblast invasion occurring with preeclampsia in humans, which makes the dog a particularly good choice for modeling this disease and will be an improvement on...