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Creator:: Smith, Samson W., Latta, Leigh C., Denver, Dee R., and Estes, Suzanne
Abstract:: BACKGROUND: The oxidative stress theory of life-history tradeoffs states that oxidative stress caused by damaging free radicals directly underpins tradeoffs between reproduction and longevity by altering the allocation of energetic resources between these tasks. We test this theory by characterizing the effects of exogenous oxidative insult and its interaction with...
Resource Type:: Article

Creator:: Hicks, Kiley A., Howe, Dana K., Leung, Aubrey, Denver, Dee R., and Estes, Suzanne
Abstract:: In We have analyzed natural variation in mitochondrial form and function among a set of Caenorhabditis briggsae isolates known to harbor mitochondrial DNA structural variation in the form of a heteroplasmic nad5 gene deletion (nad5 Delta) that correlates negatively with organismal fitness. We performed in vivo quantification of 24 mitochondrial...
Resource Type:: Article
Full Text:: . Howe2, Aubrey Leung2, Dee R. Denver2, Suzanne Estes1* 1 Biology Department, Portland State University

Creator:: Joyner-Matos, Joanna, Hicks, Kiley A., Cousins, Dustin, Keller, Michelle, Denver, Dee R., Baer, Charles F., and Estes, Suzanne
Abstract:: We explored the relationship between relaxed selection, oxidative stress, and spontaneous mutation in a set of mutation-accumulation (MA) lines of the nematode Caenorhabditis elegans and in their common ancestor. We measured steady-state levels of free radicals and oxidatively damaged guanosine nucleosides in the somatic tissues of five MA lines for...
Resource Type:: Article
Full Text:: . Hicks2., Dustin Cousins1, Michelle Keller1, Dee R. Denver3, Charles F. Baer4, Suzanne Estes2

Creator:: Clark, Katie A., Howe, Dana K., Gafner, Kristin, Kusuma, Danika, Ping, Sita, Estes, Suzanne, and Denver, Dee R.
Abstract:: Selfish DNA poses a significant challenge to genome stability and organismal fitness in diverse eukaryotic lineages. Although selfish mitochondrial DNA (mtDNA) has known associations with cytoplasmic male sterility in numerous gynodioecious plant species and is manifested as petite mutants in experimental yeast lab populations, examples of selfish mtDNA in animals...
Resource Type:: Article
Full Text:: , Dana K. Howe1, Kristin Gafner1, Danika Kusuma1, Sita Ping1, Suzanne Estes2, Dee R. Denver1* 1

Creator:: Phillips, Wendy S., Coleman-Hulbert, Anna L., Weiss, Emily S., Howe, Dana K., Ping, Sita, Wernick, Riana I., Estes, Suzanne, and Denver, Dee R.
Abstract:: Evolutionary interactions across levels of biological organization contribute to a variety of fundamental processes including genome evolution, reproductive mode transitions, species diversification, and extinction. Evolutionary theory predicts that so-called “selfish” genetic elements will proliferate when the host effective population size (N[subscrit]e) is small, but direct tests of this prediction remain...
Resource Type:: Article

Creator:: Arnold, Stevan J.
Abstract:: I explore the proposition that evolutionary biology is currently in the midst of its greatest period of synthesis. This period, which I call the Ongoing Synthesis, began in 1963 and continues at the present time. I use analysis of citations, conduct, and content to compare the Ongoing Synthesis to widely...
Resource Type:: Article
Full Text:: will summarize just two studies (Estes and Arnold 2007 and Uyeda et al. 2011), but these are

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