The myeloid-specific transcription factor, CCAAT/enhancer-binding protein epsilon (C/EBPε) is a critical mediator of myelopoiesis. Mutation of this gene is responsible for neutrophil-specific granule deficiency in humans, a condition that confers susceptibility to Staphylococcus aureus infection. We found that C/EBPε-deficient mice are severely affected by infection with S. aureus, and C/EBPε...
Dibenzo(def,p)chrysene (DBC), (also known as dibenzo[a,l]pyrene), is a high molecular weight polycyclic aromatic hydrocarbon (PAH) found in the environment, including food, produced by the incomplete combustion of hydrocarbons. DBC, classified by IARC as a 2A probable human carcinogen, has a relative potency factor (RPF) in animal cancer models 30-fold higher...
By taking advantage of the electron pathway through the heme group in cytochrome c (CytoC) electrochemists
have built sensors based upon CytoC immobilized onto metal electrodes. Previous studies have shown that the
electron transfer rate through the protein is a function of the position of this heme group with respect...
To investigate the dynamics of the Atlantic meridional overturning circulation (AMOC) on timescales longer than the observational records, model-data comparisons of past AMOC variability are imperative. However, this remains challenging because of dissimilarities between different proxy-based AMOC tracers and the difficulty of comparing these to model output. We present an...
The fatigue crack growth rates for nickel-based superalloy Haynes 282 were measured at 550, 650, and 750 °C using compact tension specimens with a load ratio of 0.1 and cyclic loading frequencies of 25 and 0.25 Hz. The crack path was observed to be primarily transgranular for all temperatures, and...
Sediment-associated microalgal biomass expressed as chlorophyll a concentration, total organic matter concentration expressed as ash-free dry weight, and hourly rates of net community primary production and community oxygen consumption were measured at monthly intervales at medium sand, fine sand, and silt sites between 0.5 and 2.0 m above MLLW during...
Northern highbush blueberry (Vaccinium corymbosum) is well adapted to acidic soils with low nutrient availability, but often requires regular applications of nitrogen (N) and other nutrients for profitable production. Typically, nutrients accumulate in the plant tissues following the same pattern as dry matter and are lost or removed by leaf...
Raspberry and blackberry (Rubus sp.) plantings have a relatively low nutrient requirement compared with many other perennial fruit crops. Knowledge of annual accumulation of nutrients and periods of rapid uptake allows for better management of fertilization programs. Annual total nitrogen (N) accumulation in the aboveground plant ranged from 62 to...