Freeze-drying, or lyophilization, has shown great promise in addressing many of the logistical challenges of storing and preserving red blood cells (RBCs). A crucial part of any RBC lyophilization protocol is the primary drying temperature, which affects the sample drying rate and the dried cake’s ability to form a stable...
One expectation of community-based participatory research (CBPR) is participant access to study results. However, reporting experimental data produced by studies involving biological measurements in the absence of clinical relevance can be challenging to scientists and participants. We applied best practices in data sharing to report the results of a study...
The boundary between ice and basalt on Earth is an analog for some near-surface environments of Mars. We investigated neutrophilic iron-oxidizing microorganisms from the basalt-ice interface in a lava tube from the Oregon Cascades with perennial ice. One of the isolates (Pseudomonas sp. HerB) can use ferrous iron Fe(II) from...
Little is known about how people living with HIV in low prevalence contexts face the challenges of stigma and
discrimination. Low prevalence and rural communities are unique environments in which HIV-related stigma
and discrimination may be intensified due to lower tolerance of differences among people and greater fear of
HIV....
Ebola virus causes an acute hemorrhagic fever lethal in primates and rodents. The contribution of host immune factors to pathogenesis has yet to be determined and may reveal efficacious targets for potential treatment. In this study, we show that the interleukin (IL)-10 signaling pathway modulates Ebola pathogenesis. IL-10 [superscript -...
BACKGROUND: Interventions to promote physical activity (PA) in children attending family child care homes (FCCHs) require valid, yet practical, measurement tools. The aim of this study was to assess the validity of two proxy report instruments designed to measure PA in children attending FCCHs. METHODS: A sample of 37 FCCH...
Indigenous cultures perceive the natural environment as an essential link between traditional cultural
practices, social connectedness, identity, and health. Many tribal communities face substantial health
disparities related to exposure to environmental hazards. Our study used qualitative methods to better
understand the Confederated Tribes of the Umatilla Indian Reservation (CTUIR) members’...
BACKGROUND: To examine the association between objectively measured light-intensity and moderate-to-vigorous-intensity physical activity (MVPA), sedentary behaviors, and biological markers in a national
sample of U.S. pregnant women, as few studies have examined these relationships among this population.
METHODS: The sample of noninstitutionalized U.S. civilians was selected by a complex, multistage...
Background: Some groups of breast cancer survivors bear a greater burden of diminished quality of life than others. Self-identified lesbians, or women who partner with other women in romantic and spousal relationships, are one group of women that has been hypothesized to experience and report poorer quality of life compared...
BACKGROUND: Parents play a significant role in shaping youth physical activity (PA). However, interventions targeting PA
parenting have been ineffective. Methodological inconsistencies related to the measurement of parental influences may be a
contributing factor. The purpose of this article is to review the extant peer-reviewed literature related to the measurement...