One expectation of community-based participatory research (CBPR) is participant access to study results. However, reporting experimental data produced by studies involving biological measurements in the absence of clinical relevance can be challenging to scientists and participants. We applied best practices in data sharing to report the results of a study...
BACKGROUND: Patients receiving hospice or palliative care often receive antimicrobial therapy; however the effectiveness
of antimicrobial therapy for symptom management in these patients is unknown.
OBJECTIVE: The study’s objective was to systematically review and summarize existing data on the prevalence and
effectiveness of antimicrobial therapy to improve symptom burden among...
Freeze-drying, or lyophilization, has shown great promise in addressing many of the logistical challenges of storing and preserving red blood cells (RBCs). A crucial part of any RBC lyophilization protocol is the primary drying temperature, which affects the sample drying rate and the dried cake’s ability to form a stable...
Significance: Parasite survival and virulence relies on effective defenses against reactive oxygen and nitrogen species produced by the host immune system. Peroxiredoxins (Prxs) are ubiquitous enzymes now thought to be central to such defenses and, as such, have potential value as drug targets and vaccine antigens. Recent Advances: Plasmodial and...
Tolerance of adult zebrafish and efficacy of emamectin benzoate and ivermectin in eliminating Pseudocapillaria tomentosa infection were evaluated. In the tolerance study, behavioral changes, fecundity, histopathology, and mortality were evaluated for in-feed administration of emamectin (0.05, 0.10, and 0.25 mg/kg) and ivermectin (0.05 and 0.10 mg/kg). All doses of emamectin...
BACKGROUND: Increasing emphasis in performance-based payment, public reporting, and quality improvement
(QI) has led to widespread interest in measuring and improving the quality of care. By 2014, hospice programs
will be required to report quality data to the federal government or incur financial penalties. With this increased
interest in quality...
Indigenous cultures perceive the natural environment as an essential link between traditional cultural
practices, social connectedness, identity, and health. Many tribal communities face substantial health
disparities related to exposure to environmental hazards. Our study used qualitative methods to better
understand the Confederated Tribes of the Umatilla Indian Reservation (CTUIR) members’...
BACKGROUND: To examine the association between objectively measured light-intensity and moderate-to-vigorous-intensity physical activity (MVPA), sedentary behaviors, and biological markers in a national
sample of U.S. pregnant women, as few studies have examined these relationships among this population.
METHODS: The sample of noninstitutionalized U.S. civilians was selected by a complex, multistage...
BACKGROUND: Interventions to promote physical activity (PA) in children attending family child care homes (FCCHs) require valid, yet practical, measurement tools. The aim of this study was to assess the validity of two proxy report instruments designed to measure PA in children attending FCCHs. METHODS: A sample of 37 FCCH...
Background: Some groups of breast cancer survivors bear a greater burden of diminished quality of life than others. Self-identified lesbians, or women who partner with other women in romantic and spousal relationships, are one group of women that has been hypothesized to experience and report poorer quality of life compared...