Otoferlin is a C2-domain, transmembrane protein whose mutated form is responsible for the DFNB9 subtype of prelingual hearing impairment. Mutations in otoferlin cause an autosomal recessive, non-syndromic form of deafness that is characterized by auditory neuropathy/ auditory dissynchrony (AN/AD), meaning that the outer hair cells (OHCs) are normal, and the...
A programming paradigm can be defined as a model or an approach employed in solving a problem. The results of the research described in this document demonstrate that it is possible to unite several different programming paradigms into a single linguistic framework. The imperative, procedural, applicative, lambda-free, relational, logic and...
Given the many significant roles that bacteria play in modern food manufacturing, it is crucial that we have a fundamental understanding of how bacterial communities assemble and behave in the food manufacturing environment. The focus of this dissertation was to investigate both the spatial and temporal distributions of microbial communities...
This dissertation investigates the effect of endogenous and exogenous events on firm behavior and performance. These are fundamental questions in economics. The contribution of this study is threefold. First, it provides estimates of the impact of mergers on railroad efficiency, which has important antitrust implications. Second, it provides new estimates...
The objectives of this research were to 1) evaluate the establishment and peak standing crop of Berber Orchardgrass (Dactylis glomerata var. "Berber"), Palestine Orchardgrass (Dactylis glomerata var. "Palestine"), and Sheep Fescue (Festuca ovina var. "Covar") ; 2) to assess establishment and production changes resulting from environmental gradients (elevation, slope, aspect,...
Aquatic insects are essential components of healthy stream ecosystems, contributing to nutrient cycling, trophic dynamics and other ecological functions. Aquatic insect species, particularly those in the orders Ephemeroptera, Plecoptera and Trichoptera (EPT taxa) are however, extremely sensitive to insecticide contamination. Given that urban and agricultural use of synthetic pyrethroid insecticides...