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Filtering by: Creator Remcho, Vincent Remove constraint Creator: Remcho, Vincent Resource Type Honors College Thesis Remove constraint Resource Type: Honors College Thesis

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  • A (3-Aminopropyl)triethoxysilane (APTES) and Glutaraldehyde Functionalized Cellulose Surface for Immunoassays

    Creator:
    Harley, William
    Abstract:
    The detection of biomolecules is critical for clinical diagnostics but requires specialty labor and high cost. The use of microfluidic paper-based analytical devices (µPADs) for bioassays is simpler and cheaper but has low sensitivity. Improved immobilization of antibodies onto cellulose is demonstrated through surface functionalization with APTES and glutaraldehyde. The...
    Resource Type:
    Honors College Thesis
    Full Text:
    :_____________________________________________________ Vincent Remcho The detection of biomolecules is critical for clinical diagnostics but requires

  • Janus-Type Wicking Microfluidic Devices for Separation and Collection of Plasma from Blood

    Creator:
    Unitan, Linus J.
    Abstract:
    A simple Janus-type membrane-based wicking microfluidic device fabricated on a polycaprolactone-filled glass microfiber membrane enables separation and collection of blood plasma or serum from whole blood. This device bridges the wicking and cut-capillary-based solution transport mechanisms in a single membrane. The initial portion of the device is fabricated using selective...
    Resource Type:
    Honors College Thesis
    Full Text:
    :_____________________________________________________ Vincent Remcho A simple Janus-type membrane-based wicking

  • Design and Fabrication of a Polymeric Microfluidic Device for Automated

    Creator:
    Warner, Kelsie E.
    Abstract:
    Gene synthesis is an important tool in molecular biology. However, the current bench-top method of gene synthesis is a costly, time-intensive and reagent-consuming process. Lab-on-chip technology has many benefits over current bench top methods. Microchips consume smaller reagent volumes, are reusable and less expensive to make. This thesis explores the...
    Resource Type:
    Honors College Thesis
    Full Text:
    for Automated Gene Synthesis. Abstract approved: Vincent T. Remcho Gene synthesis

  • Gold Nanoparticles as Thiophenol Detection Probes

    Creator:
    Pond, Emily
    Abstract:
    The development of simple, rapid, and sensitive methods for thiophenol detection is of great importance in various fields, including environmental monitoring and food quality. Here, we present a novel approach for the colorimetric detection of thiophenols using gold nanoparticles (AuNPs) as the sensing platform. AuNPs aggregate in the presence of...
    Resource Type:
    Honors College Thesis
    Full Text:
    Vincent Remcho The development of simple, rapid, and sensitive methods for thiophenol detection is of

  • Photoactuated Droplet Microfluidics

    Creator:
    Frederick, Ryan T.
    Abstract:
    A system of Photoactuated Droplet Microfluidics (PDM), in which a droplet of fluid is moved by way of the manipulation of the wettability of a spiropyran functionalized surface via irradiation with ultraviolet and visible light, was proposed. The photochromic behaviors of several species of spiropyran were studied and a procedure...
    Resource Type:
    Honors College Thesis
    Full Text:
    Approved: Vincent T. Remcho A system of Photoactuated Droplet Microfluidics (PDM), in

  • Quantification of Propofol in Blood Plasma and its Application to Future Clinical Research in Anesthesiology and Perioperative Medicine

    Creator:
    Bemis, David J.
    Abstract:
    High Performance Liquid Chromatography-Mass Spectrometry coupled with filtration, centrifugation, and other common sample preparation techniques offers a rapid and robust method for separating and quantifying propofol, a commonly used anesthetic, from human blood and its synthetic analogs. Method development is important for not only optimizing separation and quantification for a...
    Resource Type:
    Honors College Thesis
    Full Text:
    Vincent T. Remcho High Performance Liquid Chromatography-Mass Spectrometry coupled with filtration

  • Comparative Studies of Batch and Continuous Processes for the Synthesis of Copper Nanoparticles

    Creator:
    Ramsing, Patrick E.
    Abstract:
    The cross over from batch nanoparticle synthesis to continuous synthesis processes is crucial to the commercialization of these materials. This project reports comparative studies of batch and continuous synthese of copper nanoparticles by the polyol method. Continuous synthesis of copper nanoparticles was done utilizing a stainless steel micro-mixer that yielded...
    Resource Type:
    Honors College Thesis
    Full Text:
    : _____________________________________________________________________ Vincent T. Remcho The cross over from batch nanoparticle synthesis to continuous

  • Lead(II) Extraction with Electrospun Spiropyran Functionalized PMMA Nanofibers

    Creator:
    Fuchs, Brian K.
    Abstract:
    A system to reversibly extract Pb²⁺ ions from aqueous solutions using spiropyran functionalized nanofibers was proposed. Spiropyrans are photochromic compounds which undergo a conformational change that alters their physical properties and makes Pb²⁺ binding possible upon irradiation with UV light (365 nm). Irradiation with green light (525 nm) reverses this...
    Resource Type:
    Honors College Thesis
    Full Text:
    Abstract Approved: ______________________________________________ Dr. Vincent T. Remcho A system to

  • TO PAY OR NOT TO PAY, THAT IS THE QUESTION

    Creator:
    Oster, Sidney C.
    Abstract:
    The “why” of any situation is one of the most important questions to ask. Inventors have ideas every day. Some ideas are the brilliant ideas that lead to a better tomorrow. To protect these ideas, inventors turn to patents, a governmental grant of the right to stop others, for a...
    Resource Type:
    Honors College Thesis
    Full Text:
    _____________________________________________________________________ Vincent Remcho, Committee Member, representing Department of Chemistry

  • Restoring and Updating the Micralyne μTK

    Creator:
    Wong, Derek H.
    Abstract:
    The Micralyne microfluidic toolkit (μTK) was an instrument built by Micralyne in the early 2000’s. It was built for electrophoresis and has a sensitive laser-induced fluorescence detection system. The updates to the system were upgrading the control GUI from running in LabVIEW 5 (Windows XP, 2000) to LabVIEW 2012 (Windows...
    Resource Type:
    Honors College Thesis
    Full Text:
    : _____________________________________________________________________ Vincent Remcho, Mentor, representing Chemistry