Index Catalog // ScholarsArchive@OSU

Alternating Between Amperometric Copper Detection and Potentiometric Calcium Detection on a Carbon-based Ion-selective Electrode

Creator:: Park, Suji
Abstract:: The unique capability of carbon-based ion-selective electrode (ISE) to perform highly sensitive anodic stripping voltammetry, while maintaining all the properties of an ISE, is demonstrated in terms of sensitivity, detection limit, response time and selectivity. Square wave anodic stripping voltammetry involves deposition and dissolution steps of metal ions, which means...
Resource Type:: Masters Thesis
Full Text:: : _____________________________________________________________________ Claudia S. Maier The unique capability of carbon-based ion-selective electrode (ISE) to

Low-Dose X-Ray Radiation Effects On the Proteomic Profiles of Hippocampus, Cortex, and Cerebellum of Contextual Fear Conditioning and Novel Object Recognition Trained Mice

Creator:: Koluda, Rony
Abstract:: Radiation exposure to the brain can occur from a variety of events, including space missions, nuclear accidents, and clinical treatments. The effects of high dose radiation are well studied, but those of lower dosage are more elusive. Decline of memory and cognition is observed in patients exposed to low dose...
Resource Type:: Masters Thesis
Full Text:: : ______________________________________________________ Claudia S. Maier Radiation exposure to the brain can occur from a variety of events

Determination of ethyl glucuronide and ethyl sulfate as human biomarkers of alcohol exposure in urine by liquid chromatography/electrospray tandem mass spectrometry with large volume injection

Creator:: Hu, Yan
Abstract:: This research was undertaken to develop a sensitive, selective, and rapid analytical method to measure ethyl glucuronide (EtG) and ethyl sulfate (EtS) in urine as urinary biomarkers of alcohol exposure. Large-volume injection (LVI) coupled with liquid chromatography / electrospray tandem mass spectrometry was used to eliminate the need for either...
Resource Type:: Masters Thesis
Full Text:: . Claudia Maier, and Dr. Fredrick Prahl, for their advice on the dissertation content throughout the

A Graph Grammar Representation of Metal-Organic Frameworks for Computational Synthesis and Exploration

Creator:: Geringer, Mark K.
Abstract:: In this work, metal-organic frameworks (MOFs) are computationally represented, generated, and evaluated. The organic linker molecules are represented as graphs and use graph grammars where the atoms are represented by nodes and the bonds are represented by arcs. The grammar rules that dictate the graph generation process work on the...
Resource Type:: Masters Thesis

Development of materials and devices for separation of polyamido[a]mine dendrimers

Creator:: Tennico, Yolanda H.
Abstract:: Over the last decade, the use of highly branched macromolecules, called dendrimers, is emerging. Polyamidoamine (PAMAM) dendrimers, in particular, have attracted high interest due to their unique properties, such as well-defined size, shape, and solubility in water. Our group, as part of an interdisciplinary team, is currently working on developing...
Resource Type:: Masters Thesis

Opening Pandora’s Box: Machine learning applications for chemical forensics and non-target chemical analyses

Creator:: Davila-Santiago, Emmanuel
Abstract:: Water bodies act as chemical data loggers that contain tens of thousands of molecules that represent the sum of the biological, chemical, and physical processes occurring within a watershed. We hypothesize that unique chemical signatures present within a water sample can be informative of upstream processes. By extracting non-polar organic...
Resource Type:: Masters Thesis
Full Text:: Dr. Stephen Good, Dr. Claudia Maier, Dr. Jeffrey Jenkins and Dr. Lewis Semprini, my committee

Activation, incorporation and modification of capreomycidine during viomycin biosynthesis

Creator:: Fei, Xiaobo
Abstract:: Molecular genetic and enzymological techniques have been employed to study antibiotic biosynthesis. The nonproteinogenic amino acid capreomycidine is the signature residue found in the tuberactinomycin family of antitubercular peptide antibiotics and an important element of the pharmacophore. Recombinant VioG, a single module peptide synthetase from the viomycin gene cluster cloned...
Resource Type:: Masters Thesis
Full Text:: . Maier, and Dr. Rockey for their guidance and assistance throughout my graduate studies. I would like

Developing a system of mutagenesis in Francisella tularensis LVS

Creator:: Flax, Lindsay A.
Abstract:: Francisella tularensis is a gram-negative facultative intracellular coccobacillus that primarily infects macrophages. The causative agent of tularemia, this bacterium is considered among the most infectious organisms known, requiring fewer than ten organisms to cause disease. Although ubiquitous in nature, transmission to humans is rare but can occur via insect bites,...
Resource Type:: Masters Thesis
Full Text:: throughout the years. Special thanks to Dr. Claudia Häse for the hours spent discussing my project

Total Synthesis of Isotopologues of Xanthohumol and its Congeners for Biological Studies

Creator:: Plagmann, Layhna S.
Abstract:: Xanthohumol [XN, (E)-6´-methoxy-3´-(3-methylbuten-2-yl)-2´,4´,4´´-trihydroxychalcone], the principal prenylated chalcone from hops, and its 2,3-dihydro- (DXN) and O6-desmethyl-2,3-dihydro- (DDXN) congeners, are of potential utility for the amelioration of metabolic syndrome; however, their complex bioactivity profiles cannot be properly studied and understood without access to appropriately produced synthetic materials. In the first part of...
Resource Type:: Masters Thesis
Full Text:: , Claudia S. Maier, Adrian F. Gombart, Paul R. Blakemore; Journal of Labeled Compounds and

Bioinformatics applied to freshwater cyanobacterial blooms and cyanophage

Creator:: Schwartz, Andrew D.
Abstract:: Freshwater cyanobacterial blooms are a nuisance and health threat in the Pacific Northwest. The accepted methods of characterizing these blooms by microscopic cell counts cannot differentiate between toxic and non-toxic strains of the cyanobacterium Microcystis. Also, there is limited understanding of freshwater cyanophage that may control bloom dynamics. In order...
Resource Type:: Masters Thesis
Full Text:: . Bennett, Shin-Cheng Tzeng and Dr. Claudia Maier all worked with our lab to obtain excellent mass

ScholarsArchive@OSU

Alternating Between Amperometric Copper Detection and Potentiometric Calcium Detection on a Carbon-based Ion-selective Electrode

Low-Dose X-Ray Radiation Effects On the Proteomic Profiles of Hippocampus, Cortex, and Cerebellum of Contextual Fear Conditioning and Novel Object Recognition Trained Mice

Determination of ethyl glucuronide and ethyl sulfate as human biomarkers of alcohol exposure in urine by liquid chromatography/electrospray tandem mass spectrometry with large volume injection

A Graph Grammar Representation of Metal-Organic Frameworks for Computational Synthesis and Exploration

Development of materials and devices for separation of polyamido[a]mine dendrimers

Opening Pandora’s Box: Machine learning applications for chemical forensics and non-target chemical analyses

Activation, incorporation and modification of capreomycidine during viomycin biosynthesis

Developing a system of mutagenesis in Francisella tularensis LVS

Total Synthesis of Isotopologues of Xanthohumol and its Congeners for Biological Studies

Bioinformatics applied to freshwater cyanobacterial blooms and cyanophage

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