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  • Mathematical modeling and the control of immune processes with application to cancer

    Creator:
    Lee, Kwon Soon
    Abstract:
    A foundation for the control of tumors is presented, based upon the formulation of a realistic, knowledge-based mathematical model of the interaction between tumor cells and the immune system. The parametric control variables relevant to the latest experimental data, e.g., the sigmoidal dose-response relationship and Michaelis-Menten dynamics, are also considered....
    Resource Type:
    Dissertation
    Full Text:
    Immunotherapy 58 3.6 Parameter Sensitivity Analysis 64 4 SIMULATION AND RESULTS 72 4.1 Simulation and Results