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  • Fatimah Almousawi Final seminar.pdf

    Creator:
    Almousawi, Fatimah Hussain
    Abstract:
    Cancer economic impact is enormous and depending on the stage in which a colon cancer is detected, five-year survival rates for colon cancer may be as high as 74%, or as low as 6% (American Cancer Society, 2012). Thus early prevention of colon cancer is crucial to maximize the chances...
    Full Text:
    • Mutations in critical genes in DNA repair pathways • Exposure to carcinogens  Nucleotide excision

  • BRR Thesis- Fatimah Almousawi final.pdf

    Creator:
    Almousawi, Fatimah Hussain
    Abstract:
    Cancer economic impact is enormous and depending on the stage in which a colon cancer is detected, five-year survival rates for colon cancer may be as high as 74%, or as low as 6% (American Cancer Society, 2012). Thus early prevention of colon cancer is crucial to maximize the chances...
    Full Text:
    repair (MMR), or nucleotide excision repair (NER) are associated with increased cancer risk. We

  • Fatimah Almousawi Final seminar.pptx

    Creator:
    Almousawi, Fatimah Hussain
    Abstract:
    Cancer economic impact is enormous and depending on the stage in which a colon cancer is detected, five-year survival rates for colon cancer may be as high as 74%, or as low as 6% (American Cancer Society, 2012). Thus early prevention of colon cancer is crucial to maximize the chances...
    Full Text:
    in critical genes in DNA repair pathways • Exposure to carcinogens Nucleotide excision repair (XP

  • MathewsDeoxyribonucleotideMetabolismMutagenesisAndCancerFigures1-5.pdf

    Creator:
    Mathews, Christopher K.
    Abstract:
    Cancer was recognized as a genetic disease at least four decades ago, with the realization that the spontaneous mutation rate must increase early in tumorigenesis, to account for the many mutations in tumor cells as compared with their progenitor normal cells. The genetic basis for cancer was established also from...
    Full Text:
    reductase and dCMP deaminase shown to be mutagenic141 1992 Nucleotide pool “sanitation” shown to

  • MathewsDeoxyribonucleotideMetabolismMutagenesisAndCancer.pdf

    Creator:
    Mathews, Christopher K.
    Abstract:
    Cancer was recognized as a genetic disease at least four decades ago, with the realization that the spontaneous mutation rate must increase early in tumorigenesis, to account for the many mutations in tumor cells as compared with their progenitor normal cells. The genetic basis for cancer was established also from...
    Full Text:
    authors to suggest that the base excision repair pathway is more efficient than nucleotide pool

  • Deoxyribonucleotide Metabolism, Mutagenesis, and Cancer

    Creator:
    Mathews, Christopher K.
    Abstract:
    Cancer was recognized as a genetic disease at least four decades ago, with the realization that the spontaneous mutation rate must increase early in tumorigenesis, to account for the many mutations in tumor cells as compared with their progenitor normal cells. The genetic basis for cancer was established also from...
    Resource Type:
    Article