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McDougallLipidomicsandH2180OLabeling.pdf

Creator:: McDougall, Melissa Q., Choi, Jaewoo, Stevens, Jan F., Truong, Lisa, Tanguay, Robert L., and Traber, Maret G.
Abstract:: We hypothesized that vitamin E (α-tocopherol) is required by the developing embryonic brain to prevent depletion of highly polyunsaturated fatty acids, especially docosahexaenoic acid (DHA, 22:6), the loss of which we predicted would underlie abnormal morphological and behavioral outcomes. Therefore, we fed adult 5D zebrafish (Danio rerio) defined diets without...
Full Text:: deficient zebrafish (danio rerio) embryos Melissa Q. McDougall a,b, Jaewoo Choi a, Jan F. Stevens a,c,f

McDougallLipidomicsandH2180OLabelingSupplement.pdf

Creator:: McDougall, Melissa Q., Choi, Jaewoo, Stevens, Jan F., Truong, Lisa, Tanguay, Robert L., and Traber, Maret G.
Abstract:: We hypothesized that vitamin E (α-tocopherol) is required by the developing embryonic brain to prevent depletion of highly polyunsaturated fatty acids, especially docosahexaenoic acid (DHA, 22:6), the loss of which we predicted would underlie abnormal morphological and behavioral outcomes. Therefore, we fed adult 5D zebrafish (Danio rerio) defined diets without...

Lipidomics and H₂¹⁸O labeling techniques reveal increased remodeling of DHA-containing membrane phospholipids associated with abnormal locomotor responses in α-tocopherol deficient zebrafish (danio rerio) embryos

Creator:: McDougall, Melissa Q., Choi, Jaewoo, Stevens, Jan F., Truong, Lisa, Tanguay, Robert L., and Traber, Maret G.
Abstract:: We hypothesized that vitamin E (α-tocopherol) is required by the developing embryonic brain to prevent depletion of highly polyunsaturated fatty acids, especially docosahexaenoic acid (DHA, 22:6), the loss of which we predicted would underlie abnormal morphological and behavioral outcomes. Therefore, we fed adult 5D zebrafish (Danio rerio) defined diets without...
Resource Type:: Article

Using Mass Spectrometry to Trace Polyphenols in Human Urine

Creator:: Carrillo, Crystal V.
Abstract:: Diet History Questionnaires (DHQ) can only provide general information about a person’s nutritional intake. It is unable to cluster groups of people based on diets or lifestyles, nor identify specific foods that may play a role in disease prevention. The aim of this study was to validate the use of...
Resource Type:: Presentation and Undergraduate Thesis
Full Text:: thanks to Fred Stevens, Jaewoo Choi, Sandra Uesegui, Rachel Hahn, and Gerd Bobe for aiding in proper

Novel liquid chromatography–mass spectrometry method shows that vitamin E deficiency depletes arachidonic and docosahexaenoic acids in zebrafish (Danio rerio) embryos

Creator:: Lebold, Katie M., Kirkwood, Jays S., Taylor, Alan W., Choi, Jaewoo, Barton, Carrie L., Miller, Galen W., La Du, Jane, Jump, Donald B., Stevens, Jan Frederik, Tanguay, Robert L., and Traber, Maret G.
Abstract:: To test the hypothesis that embryogenesis depends upon α-tocopherol (E) to protect embryo polyunsaturated fatty acids (PUFAs) from lipid peroxidation, new methodologies were applied to measure α-tocopherol and fatty acids in extracts from saponified zebrafish embryos. A solid phase extraction method was developed to separate the analyte classes, using a...
Resource Type:: Article
Full Text:: (Danio rerio) embryos$ Katie M. Lebold a,b, Jay S. Kirkwood a,c, Alan W. Taylor a, Jaewoo Choi a, Carrie

Homeodomain Transcription Factor Pitx2 is Required for Muscle Maintenance and Energy Homeostasis

Creator:: Lattier, Vera C.
Abstract:: Skeletal muscle, the largest organ in the body in mass, is composed by 600 specialized muscles in humans with unique biochemical, physiological and metabolic identities. Skeletal muscles control body movement, locomotion, and nutrient balance. Muscle formation requires precisely orchestrated environmental signals and regulatory gene networks in time and space. Gene...
Resource Type:: Dissertation

Vitamin E Protects Developmental Gene Expression and Metabolic Networks in Zebrafish Embryos

Creator:: Head, Brian A.
Abstract:: Vitamin E (VitE) is necessary for vertebrate embryonic development. VitE prevents lipid peroxidation (LPO), which requires detoxification by cellular antioxidant systems subsequently involving reducing power derived from energy metabolism. Thus, VitE protects metabolic networks in the developing embryo and the integrated gene expression networks compensating for and impaired by LPO-induced...
Resource Type:: Dissertation
Full Text:: without your guidance. To Dr. Jaewoo Choi, your expertise is unmatched, and Sandra Uesugi, your office

Comparative lipid profiling of human stratum corneum between atopic dermatitis and healthy subjects

Creator:: Stewart, Shelby L.
Abstract:: Dermatological issues are a widespread problem in humans that are often overlooked. In our present study, we have isolated lipids from de-identified epidermal skin tape samples from both Atopic Dermatitis and healthy individuals using a high efficiency one-step extraction method, which were subsequently analyzed using modified Liquid chromatography–mass spectrometry (LC-MS)....
Resource Type:: Honors College Thesis
Full Text:: Pauling Institute for his collaboration with this project and Jaewoo Choi at the Linus Pauling Institute

Developing a Method For Quantitation of Organic Acid Exometabolites Released By Streptococcus mutans Biofilm Grown Under Oral Cavity-like Conditions

Creator:: Akmal, Ryaan
Abstract:: Tooth decay in the form of dental caries and cavities is estimated to be among the most common health conditions globally, with treatment of these oral diseases resulting in a massive, world-wide economic burden. The cause of this demineralization of teeth is rooted in the action of complex microbial biofilms...
Resource Type:: Honors College Thesis
Full Text:: with sample preparation and the use of their instrumentation equipment, including Dr. Jaewoo Choi

High efficiency wideband low-power delta-sigma modulators

Creator:: Lee, Sang Hyeon
Abstract:: Delta-sigma analog-to-digital converters traditionally have been used for low speed, high resolution applications such as measurements, sensors, voice and audio systems. Through continued device scaling in CMOS technology and architectural and circuit level design innovations, they have even become popular for wideband, high dynamic range applications such as wired and...
Resource Type:: Dissertation
Full Text:: . To my parents Jaewoo Lee and Kyungae Kim, my in-laws Dalsik Choi and Sookja Kwon, my wife Yeon

ScholarsArchive@OSU

McDougallLipidomicsandH2180OLabeling.pdf

McDougallLipidomicsandH2180OLabelingSupplement.pdf

Lipidomics and H₂¹⁸O labeling techniques reveal increased remodeling of DHA-containing membrane phospholipids associated with abnormal locomotor responses in α-tocopherol deficient zebrafish (danio rerio) embryos

Using Mass Spectrometry to Trace Polyphenols in Human Urine

Novel liquid chromatography–mass spectrometry method shows that vitamin E deficiency depletes arachidonic and docosahexaenoic acids in zebrafish (Danio rerio) embryos

Homeodomain Transcription Factor Pitx2 is Required for Muscle Maintenance and Energy Homeostasis

Vitamin E Protects Developmental Gene Expression and Metabolic Networks in Zebrafish Embryos

Comparative lipid profiling of human stratum corneum between atopic dermatitis and healthy subjects

Developing a Method For Quantitation of Organic Acid Exometabolites Released By Streptococcus mutans Biofilm Grown Under Oral Cavity-like Conditions

High efficiency wideband low-power delta-sigma modulators

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