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  • Chronic Toxicological Effects in Daphnia magna from Exposure to PMMA Nanoplastics

    Creator:
    Brown, Hans
    Abstract:
    Plastic pollution is an ever-increasing environmental threat. As large-scale plastics break down to form nanoscale plastics, it is essential to investigate their effects on freshwater ecosystems. With many plastic nanoparticle (NP) studies favoring the effects of common polystyrene (PS) plastics, a gap is formed for other common plastic types like...
    Resource Type:
    Honors College Thesis
    Full Text:
    approved: _____________________________________________________ Stacey Harper Plastic pollution is an

  • Developmental effects of micro- and nanoscale tire particles and recycled rubber on zebrafish

    Creator:
    Mottern, Taylor H.
    Abstract:
    Plastics have become an essential part of everyone lives, found in almost every product made today. Tires only make up a fraction of these products but as their use increasing so does the microplastics that flake off. Many studies have evaluated the toxic effects of tire particles on aquatic environments...
    Resource Type:
    Honors College Thesis
    Full Text:
    rubber on zebrafish. Abstract approved: Stacey Harper Plastics have become an essential

  • Making Science Accessible

    Creator:
    Renda, Ashley R.
    Abstract:
    My work in the Harper Nanotoxicology Lab focuses on science communication. The Harper Lab conducts research to address data gaps regarding the toxicity of micro and nanoplastic in the environment, specifically in aquatic habitats. It is important for the public to understand what the lab does, and how they can...
    Resource Type:
    Video

  • Environmental Transformations in Hydrophobicity of TiO2 P-25 Nanoparticles in Alsea River Waters

    Creator:
    Boenisch, Kylie
    Abstract:
    Hydrophobic titanium dioxide (TiO2) nanoparticles (NPs) are prevalent in industry and manufacturing. They are known for their white pigmentation, are found in sunscreens, paints, cosmetics, and are frequently used in wastewater treatment. Understanding the physicochemical properties of TiO2 P-25 NPs, such as hydrophobicity, are essential when determining their fate, transport,...
    Resource Type:
    Honors College Thesis
    Full Text:
    :_____________________________________________________ Stacey Harper Hydrophobic titanium dioxide (TiO2) nanoparticles (NPs) are prevalent in

  • Assessing Changes in Biological Interactions of Lipid-Coated Gold and Silver Nanoparticles Based on Physicochemical Properties

    Creator:
    Engstrom, Arek Mackenzie
    Abstract:
    Nanoparticles (NPs), particles defined by their size in a single dimension (1-100 nm), are being increasingly incorporated into commercial and industrial products due to their high surface area to volume ratio that gives them unique properties, such as optical tunability and higher reactivity than their bulk counterparts. NPs can be...
    Resource Type:
    Masters Thesis
    Full Text:
    Stacey L. Harper Nanoparticles (NPs), particles defined by their size in a single dimension (1

  • Optimizing Methods to Assess Nanoparticle Biodistribution in Embryonic Zebrafish

    Creator:
    Pfarr, Shaylin H.
    Abstract:
    As nanoparticle (NP) research and development expands, the significance of NP biodistribution effects on toxicity increases. A reliable method for measuring NP biodistribution is critical. Hyperspectral Imaging (HSI) is capable of accurately quantitating NP biodistribution within embryonic zebrafish with incredibly high precision. Before HSI processing, the embryo must be sectioned...
    Resource Type:
    Honors College Thesis
    Full Text:
    : _____________________________________________________ Stacey Harper As nanoparticle (NP) research and development expands, the significance

  • Reduced toxicity of benzethonium chloride to Escherichia coli through adsorption onto titanium dioxide nanoparticles

    Creator:
    Waldron, Kerri Raven
    Abstract:
    Antimicrobial agents are being increasingly used in consumer soaps and detergents, despite a lack of data demonstrating their efficacy in such products. This study investigated the nature of the interaction between different crystalline structures of titanium dioxide nanoparticles and BTC, and explore which structure, if any, could be best used...
    Resource Type:
    Honors College Thesis
    Full Text:
    Approved: _____________________________________________________ Stacey Harper Antimicrobial agents

  • Comparative toxicological assessment of PAMAM and thiophosphoryl dendrimers using embryonic zebrafish.

    Creator:
    Pryor, Joseph Brian
    Abstract:
    Dendrimers are well-defined, polymeric nanomaterials currently being investigated for their biomedical applications. Initially, higher generation (size) dendrimers were of interest because of their drug carrying capacity. However, increased generation was associated with increased toxicity. The objective of the present study was to investigate the role of surface charge and generation...
    Resource Type:
    Honors College Thesis
    Full Text:
    : ______________________________________________ Stacey Harper Dendrimers are well-defined, polymeric nanomaterials

  • Assessing the toxicity of nanoplastics using the primary human bronchial epithelial model

    Creator:
    Germano, Francesca
    Abstract:
    Emerging data showing the presence of atmospheric microplastics (MPs) has recently raised awareness surrounding the potential of human nanoplastics (NPs) exposure. Due to factors such as weathering, UV exposure, and other biodegradation processes, plastic pollution in the environment breaks down over time into micro (<5 micrometers) and nanoscale (<1000nm) particles....
    Resource Type:
    Masters Thesis
    Full Text:
    and Stacey Harper Emerging data showing the presence of atmospheric microplastics (MPs) has

  • Addressing the Risks of Nanoscale Polymers: Exposure, Behavior, and Toxicity

    Creator:
    Stine, Jared
    Abstract:
    Nanoscale polymers (including nanoplastics) are widely present through commerce and make their way into the environment. As the improper disposal of plastic waste leads to continued accumulation and degradation of plastic pollution, the presence of plastic particles less than 1 micron (μm) in size (nanoplastics) will increase. Heightened concern over...
    Resource Type:
    Dissertation
    Full Text:
    approved: ______________________________________________________ Stacey L. Harper Nanoscale