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Filtering by: Committee Member Gehler, Jan L. Subject Alcoholic liver diseases

Label-free mass spectrometry-driven methods for elucidating adaptive responses of the hepatic mitochondrial proteome in an alcoholic fatty liver disease model

Creator:

Tzeng, Shin-Cheng

Abstract:

Alcoholic liver disease (ALD) continues to be one of the major public health problems in the United States and worldwide. Complicated by factors including gender, polymorphisms of alcohol-metabolizing enzymes, immunologic factors, exposures to other substances/drugs, hepatic viral infections, nutritional deficiencies, and obesity, ALD is a complex disease that requires a...

Resource Type:

Dissertation

Full Text:

Introduction (part of the chapter was adapted from Vasil'ev, Y. V.; Tzeng, S. C.; Huang, L.; Maier, C. S