Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Creator Wang, Chao-huan Subject Bacteriophage T4

Organization of T4 bacteriophage genes and gene products involved in DNA precursor biosynthesis

Creator:

Wang, Yeong

Abstract:

Bacteriophage T4 gene 42 encodes dCMP hydroxymethylase, an enzyme unique to the deoxyribonucleotide metabolism of T-even bacteriophages. To study biochemical and biophysical properties of the enzyme, as well as the interaction of dCMP hydroxymethylase with other DNA precursor biosynthetic enzymes in vitro, availability of large amounts of the enzyme is...

Resource Type:

Dissertation

Full Text:

involved in DNA precursor biosynthesis AN ABSTRACT OF THE THESIS OF Yeong Wang for the degree of Doctor
Mutagenic mechanisms associated with perturbations of DNA precursor biosynthesis in phage T4

Creator:

Ji, Jiuping

Abstract:

A crucial factor in determining the accuracy of DNA replication is maintenance of a balanced supply of deoxyribonucleoside triphosphates (dNTPs) at replication forks. Perturbation of dNTP biosynthesis can induce dNTP pool imbalance with deleterious genetic consequences, including increased mutagenesis, recombination, chromosomal abnormalities and cell death. Using the T4 bacteriophage system,...

Resource Type:

Dissertation

Full Text:

Affi -Gel, Wang (1989) has identified several dNTP biosynthesis enzymes as well as DNA replication
Protein-protein interactions in the bacteriophage T4-coded dCTPase-dUTPase

Creator:

Ungermann, Christian

Resource Type:

Masters Thesis

Full Text:

intracellular interaction of these enzymes (Chao et al., 1977). dCMP deaminase (gpcd) This hexameric enzyme
Nucleoside diphosphokinase of Escherichia coli and its interactions with bacteriophage T4 proteins of DNA synthesis

Creator:

Ray, Nancy Bisset

Resource Type:

Dissertation

Full Text:

suppresses a gene 42 (dCMP hydroxymethylase) mutation (Chao et al, 1977) and the expression of nrdB (small
Bacteriophage T4 ribonucleotide reductase : genes and proteins

Creator:

Hanson, Eric Scott

Resource Type:

Dissertation