Recent sensor System-on-Chips (SoC) have enabled significant advances in energy-efficiency by incorporating various micro-powered building blocks. Unfortunately, most of these sensor systems do not address the high power cost associated with data storage and transmission, which in some cases vastly exceeds the power consumed by the rest of the SoC....
The Brain Research through Advanced Innovative Neurotechnologies (BRAIN) initiative seeks to understand how ensembles of neurons create neural networks. The initiative has spurred the pursuit of developing novel experimental tools for investigating how individual neurons propagate electrical signals (action potentials) to produce ensemble behavior. Classical techniques to measure the internal...
We demonstrated a sensitive biosensor based on plasmonic metal composite nanostructures. The device can be fabricated and duplicated with ease using a novel nanoprinting technology which allows precise transfer of metal nanostructures without complicated lithography processes. The design featured by its unique material composition and sub-wavelength structures maximizes the exposure...
This work describes the development of an accurate, low-cost, expandable and wearable health and activity monitoring platform. Wearable monitors used to track physical activity are becoming an increasingly popular and effective way to combat our dangerously sedentary lifestyles. Unfortunately most existing wearable solutions are either costly, inaccurate or cumbersome. The...
Bud break is a key adaptive trait that can help us understand how plants respond to a changing climate from the molecular to landscape scale. Despite this, acquisition of bud break data is currently constrained by cost, scale, and a lack of information at the plant scale on the environmental...
A label-free, photoluminescence (PL) based biosensor for 2,4,6-trinitrotoluene (TNT) detection was developed by functionalizing diatom biosiilica with a TNT-specific single-chain variable fragment (scFv). The scFv loading was estimated to be 0.040±0.003 (μg scFv/μg biosilica). In saturated concentration, TNT binding to scFvbiosilica quenched about 13% of its PL. Dose response follows...
The release of the IEEE802.15.6 standard has led to increased interest in low-power technologies for wireless body-area-networks (WBANs). The power dissipation, supply voltage, and die area are some of the most important criteria for successful WBAN implementations. Digital-intensive RX architectures can potentially result in sub-1V operation with significant reductions in...
Since their discovery in the 1990s, the great potential of carbon nanotubes (CNTs) has made them a focus of many research endeavors, including their application as components of biosensors. The inherent chemical "inertness" of CNTs makes their application to biosensing a challenge. It is necessary to "decorate" their surfaces to...
Bacterial contamination of food poses a great risk to human health worldwide. A
chromatophore cell-based biosensor, utilizing B. splendens erythrophore cells, is an
emerging technology that has shown potential to detect bacterial toxicity based on
function-dependent mechanisms. Previous studies have investigated the response of
erythrophore cells to foodborne pathogens, pesticides,...
The proliferation of body worn autometric devices has been enabled by advances in low-power electronics and fueled by the quantified-self movement. These devices range in complexity from pedometers to clinical vital sign measurement. They all share the same drawback, typically the most expensive and heaviest component, the battery. The future...