Indole-3-carbinol (I3C) inhibits chemically induced tumor
formation in rodents and rainbow trout. This study examines the
effect of I3C and its analog, indole-3-acetonitrile (I3N) on
xenobiotic-metabolizing enzyme systems. The modulation of these enzyme
systems have been shown to have significant effects on the
interaction of chemical carcinogens and cellular constituents....