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Filtering by: Creator Luo, Ming-Cheng Remove constraint Creator: Luo, Ming-Cheng Subject Transcription factors Remove constraint Subject: Transcription factors

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  • Modulation of metabolic syndrome by soy isoflavones : in-vitro and in-vivo models

    Creator:
    Luo, Ting
    Abstract:
    Metabolic syndrome is a problem affecting people around the world. In a number of studies, soy intake has been documented to possess antidiabetic and anticardiovascular effect. My project is focused on the impact of the intake of compounds found within soy, the isoflavones, their impact on metabolic syndrome symptoms, and...
    Resource Type:
    Dissertation
    Full Text:
    AN ABSTRACT OF THE DISSERTATION OF Ting Luo for

  • Roles of homeodomain transcription factors during organogenesis

    Creator:
    Xu, Jun
    Abstract:
    The spatial and temporal patterning of sequence specific transcription factors (SSTFs) contributes to cell type specification and organ formation during embryogenesis. Homeodomain transcription factors are evolutionally conserved among invertebrate and vertebrate animals. They are responsible for body segmentation and organogenesis. Lbx1 and Pitx2 both are homeodomain transcription factors contributing to...
    Resource Type:
    Dissertation
    Full Text:
    committed to diverse cellular fates (Cheng et al., 2005, Brohl et al., 2008, Huang et al., 2008). It has

  • Transcriptional repression by CTIP2, a C2H2 zinc finger protein

    Creator:
    Topark-Ngarm, Acharawan Khamsiritrakul
    Abstract:
    CTIP2, a novel C2H2 zinc finger protein, is a transcriptional repressor that functions by at least two mechanisms. CTIP2 interacts with and stimulates transcriptional repression mediated by COUP-TF family members. CTIP2 also represses transcription independently of COUP-TF proteins by direct, sequence-specific DNA binding activity. CTIP2 has been implicated in lymphoid...
    Resource Type:
    Dissertation
    Full Text:
    apoptosis (Luo et al., 2000). FOG-1 recruits the NuRD complex to mediate transcriptional repression of its

  • Gene networks during cardiogenesis and skeletal myogenesis

    Creator:
    Ma, Hsiao-Yen
    Abstract:
    Organismal development requires a precisely orchestrated transcriptional program to correctly deploy genetic information into the genome. This process requires sophisticated gene regulatory networks at multiple spatial and temporal levels from early embryonic development to adult physiological conditions. Molecular differences that define cell types are set up during the pattern formation...
    Resource Type:
    Dissertation

  • Gene regulatory networks during muscle development

    Creator:
    Eng, Diana G.
    Abstract:
    Congenital myopathies are caused by heritable mutations in particular genes. Genes mutated in congenital muscular dystrophies often encode cytoskeletal proteins, which contribute to the shape and movement of cells. We would like to know how such molecular defects lead to the muscle weakness in patients. It is therefore important to...
    Resource Type:
    Dissertation
    Full Text:
    . Dev Dyn 218, 195-200. 10 Huang, Y., Guigon, C.J., Fan, J., Cheng, S.Y., and Zhu, G.Z. (2010