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Filtering by: Creator Whitehead, John Subject Vaccinia

Proteolytic maturation of Vaccinia virus structural proteins : enzyme and substrate analysis

Creator:

Whitehead, Stephen S.

Resource Type:

Dissertation

Full Text:

proteins : enzyme and substrate analysis AN ABSTRACT OF THE THESIS OF Stephen S. Whitehead for the
Proteolytic maturation of vaccinia virus structural proteins

Creator:

VanSlyke, Judy K.

Abstract:

Vaccinia virus (VV) is a large DNA virus belonging to the Orthopoxvirus family. The viral replicative life cycle takes place solely within the cytoplasm of a mammalian host cell. The VV genome contains 196 open reading frames which are expressed in a highly regulated and temporal fashion in order to...

Resource Type:

Dissertation

Full Text:

Whitehead for his collaborative teamwork, humor, and comradery (and ability to drive a van with or without
Palmitylation of vaccinia virus proteins : identification of modification sites and biological relevance

Creator:

Grosenbach, Douglas W.

Abstract:

Vaccinia virus encodes at least eight proteins that are modified post-translationally by the addition of a 16-carbon saturated fatty acid through thioester linkage to cysteine residues. This is referred to as palmitylation of proteins. The purpose of this work was to gain an understanding of palmitylation, focusing on what defined...

Resource Type:

Dissertation
Evidence for the modification of vaccinia virus core proteins by ADP-ribosylation

Creator:

Child, Stephanie J.

Abstract:

Vaccinia virus (VV), the prototype member of the orthopoxvirus family, is a large virus of complex morphology which contains a 191 Kbp double-stranded DNA genome whose expression is tightly regulated in a temporal fashion during viral replication. The regulation of gene expression can be exerted at various of levels, including...

Resource Type:

Dissertation

Full Text:

and science. Sincerest thanks also to Pei-Yu Lee, Monica Ravanello, Steve Whitehead, Barb Hettinger