During catalysis the flavoprotein domain of neuronal nitric-oxide synthase (nNOS) shuttles NADPH-derived reducing equivalents from FAD to FMN and then to the P450-heme enabling heme-based oxygen activation and subsequent NO-synthesis. The binding of Ca²⁺-activated calmodulin (Ca²⁺-CaM) to nNOS alleviates inhibition of flavin mediated electron transfer within the diflavin domain, which...
This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of thirteen new secondary metabolites, the isolation of over fifteen previously reported metabolites and the biosynthetic investigation of two additional cyanobacterial compounds. Two novel lipopeptides were identified from a Lyngbya majuscula and Schizothrix sp. assemblage...
It has been held that heuristic training alone is not enough for developing one's mathematical thinking. One missing component is a mathematical point of view. Many educational researchers have proposed problem-based curricula to improve students' views of mathematical thinking. The present study reports findings regarding effects of a problem-based calculus...
The purpose of the present study was to investigate the moderating role of hedonic shopping value in shopping experience satisfaction in the context of clothing shopping. Hedonic shopping value is an emotional and hedonic appreciation of shopping. According to the existing literature, consumers' hedonic shopping value is associated with several...
There has been a growing interest in eating disorders among Singaporean medical professionals since the 1990s, and the Singaporean public is also starting to become aware of the risks of these conditions. This ethnographic research on eating disorders in Singapore, conducted in 2001, however, found that the majority of the...
Several popular cultural movements emphasizing indigenous spirituality have arisen in the United States and Europe within the past thirty years. Spiritual discourses attributed to Native Americans, among other groups, are borrowed by Euro-Americans in search of alternatives to dominant ideologies. In such a circumstance, Native Americans become part of a...
The controversial condition of carbohydrate craving is believed by some
researchers to be a defect in the regulation of food intake by an individual.
This defect is believed to be responsible for the inability of some persons to
control their food intake and therefore their weight. Research was conducted
to...