Altogether, this dissertation highlights the value of mass spectrometry-based analysis of intact proteins for solving problems related to understanding disease mechanisms and developing new therapeutics.
Mutations to the antioxidant enzyme Cu, Zn Superoxide Dismutase (SOD1) perturb protein structure in vivo to cause 2-5% of amyotrophic lateral sclerosis (ALS) cases. Metal-deficient...
Funk’s (1991) cockpit task management (CTM) theory is structurally consistent with cognitive multitasking models: it addresses managing multiple and concurrent tasks in three stages: situation awareness, response selection, and response execution. Based on CTM theory, Colvin, Funk and Braune (2005) hypothesized that the following six factors may affect task prioritization:...
In this dissertation, my research work on excited state dynamics of small organic molecules in solutions is presented. Using femtosecond stimulated Raman spectroscopy (FSRS) as the main experimental tool, the excited state hydrogen-bonding dynamics (ESHBD) of Coumarin 102, a common laser dye molecule, in ethanol solution is examined with <150...
Both Leperisinus oregonus and L. californicus are bark beetle
species which emerge from Fraxinus latifolia brood logs as sexually
immature adults and disperse to living ash. Occasional field observations suggest that, for overwintering and maturation feeding, L.
oregonus enter trunks and branches, whereas L.; californicus enter twig
crotches, buds and...
This dissertation investigates livelihood and land use change dynamics in a community at the farm-forest periphery in highland Ethiopia. I use interviews and livelihood assessment data to compare the strategies used by members of different wealth groups to negotiate and maintain access to forest resources, and integrate socioeconomic, bio-physical and...