Reported here is an investigation to determine the in vitro and in vivo metabolism
of xanthohumol (XN). XN is the major prenylated flavonoid of the female
inflorescences (cones) of the hop plant (Humulus lupulus). It is also a constituent of
beer, the major dietary source of prenylated flavonoids. Recent studies...
This thesis details my investigation of some pharmaceuticals and natural products on the transport of drugs which are substrates of P-glycoprotein (P-gp), such as cyclosporin A (CSA) and digoxin by using Caco-2 and MDCKII-MDR1 drug transport models. Three objectives were performed to address this goal. The first objective was to...
This study was designed to confirm or refute the tenderizing
effect of ultra-hydrostatic pressure on warm excised pre-rigor
muscle, plus to take a thorough look at its effect on some meat
characteristics of economic importance.
Samples for the experiment were obtained from animals (cattle
and sheep) slaughtered at Oregon State...
Electrical stimulation of beef carcasses (n=18) did not cause a
significant reduction in microbial population on three different sampling
positions immediately following slaughter. In constrast, significant
microbial reduction (P > 0.05) was found at position 2 (muscle
above aitch bone), but not at position 1 (inside of neck) or position...
Little is known about the fall and winter ecology of hibernating bats in western North America. Filling knowledge gaps for these populations has become more urgent with the westward spread of the white-nose syndrome, a disease that infects bats during hibernation. Due to the thermal requirements of the fungal pathogen...
Successful cryopreservation of bone marrow in situ within vertebral bodies offers an opportunity for quick and convenient storage of a significant quantity of bone marrow stem cells, including hematopoietic- and mesenchymal-type stem cells. However, cryopreservation of more complex large tissues and organs, such as the vertebral body (VB), remains problematic....
On a global scale, potato (Solanum tuberosum L.) plays an important role in tackling the threat of food insecurity due to its high yield and broad global acceptance. However, pathogens threaten potato production, causing direct yield loss and rendering potatoes tubers unmarketable. Breeding new cultivars that carry multiple resistances is...
The spread of nonnative species across the globe has contributed to biodiversity loss and changes in ecosystem structure and function. Monitoring the introduction, naturalization, and spread of introduced species is critical in abating negative impacts wrought by species invasions. However, providing basic information concerning the presence or spread of many...
Young children with developmental disabilities (< 12 years old) participate less in physical activity (PA) and experience motor skill deficits compared to young children without disabilities (Jung, Leung, Schram, & Yun, 2018; Liu, Hamilton, Davis, & ElGarhy, 2014; Whyatt & Craig, 2012). When taking account of a bi-directional relationship between...