Signal transduction within and between cells is at the core of biological activity in all living systems. Signaling networks are required for regulating biological functions, including growth, development and survival. Deregulation of signaling cascades has been linked to chronic and acute diseases and disorders This thesis focuses on mass spectrometry...
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Trypsin -K,R-|-X, not -K,R-|-P
LysC -K-|-X
GluC -E-|-X, much slower -D-|-X
AspN -X-|-D and -X
Numerous studies have explored how alluvial channel size and morphology are adjusted to different sediment and flow conditions, yet we still know very little about how and to what degree the flow regime controls channel form and processes. We use the term ‘channel form’ to refer to the size and...
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4.3.5 1-D Sediment Transport Modeling
The objective of this study is to evaluate the potential of removing organic carbon and inorganic nitrogen contaminants, and metals from the leachate prior to any land application. New guidelines are needed to ensure the environment and our health is not put at risk. The cost of installation, operation and...
A comparative study of three six-axis force sensors selected after an extensive literature survey is presented. A sensor to measure ground contact force at each foot of a walking machine is recommended.
Principles of force sensing are reviewed and characteristics of sensing elements are discussed. Results of simulation of three...
Gamma Ray Bursts (GRBs) are the most energetic explosions in the Universe, producing up to $\sim10^{53}$ ergs of energy in the first few seconds of their emission -- the so-called prompt phase that is dominated by high energy X-ray and $\gamma$-ray photons. The very large luminosities released in these events...
In recent years, the role of the City Manager in municipal
policy making has been the focus of considerable attention and debate in
both the academic and local government arenas. The purpose of this
study was to determine the differences in views of elected mayors and
appointed managers with regard...
In 2012, Oregon began it enrolling its Medicaid beneficiaries in an accountable care model called Coordinated Care Organizations (CCOs). As one of the of the earliest state-wide efforts to implement this type of healthcare reform among Medicaid enrollees, and thus one of the most mature, Oregon’s CCO implementation provided a...
Pre-spawning mortality (PSM) presents a major problem for population recovery of spring Chinook salmon (Oncorhynchus tshawytscha) in the Willamette River basin. In certain reaches and years, PSM has exceeded 90%. Histology has been used as the primary diagnostic method to investigate PSM in the Chinook Salmon, and a collection of...
Polycyclic aromatic hydrocarbons (PAHs) are complex mixtures that form when organic matter is burned. Humans are primarily exposed to PAHs via air pollution from incomplete combustion of fossil fuels and biomass, such a motor vehicle exhaust, cigarette smoke, wood smoke, or industrial emissions; or via ingestion of PAHs bound to...