The standard interpretation of quantum mechanics (known as the Copenhagen interpretation) divides the world into quantum phenomena and classical observers that perform measurements upon the phenomena. This provides a quite functional framework for calculating probabilities of measurement outcomes, but it lacks the generality necessary for such things as retrodiction, and...
Blastocystis spp. is a common intestinal parasite in humans and animals that has been associated with acute or chronic digestive disorders such as irritable bowel syndrome. Serotonin mediates intestinal motility, sensation, and secretory function in the normal intestinal tract. Serotonin (5-HT) signaling is decreased in animal models of colitis, as...
The pyrrolizidine alkaloids (PAs) and ergot alkaloids are known natural toxicants found in livestock forage. These alkaloids contribute to large economic losses in livestock throughout the world. An understanding of the mechanisms of toxicity and development of better diagnostic tools for better management practices was investigated. Variability exists in the...
Cyclic nitramines released into all environmental compartments through anthropogenic activities are toxic and possibly carcinogenic and mutagenic. Soils on military ranges, located throughout the world in various climatic regions and close to human activities, are especially susceptible to cyclic nitramine contamination. The properties of soils on military ranges will directly...
A study was conducted to evaluate the developmental toxicity of three commonly detected mycotoxins in food (deoxynivalenol, patulin, and zearalenone) using the zebrafish (Danio rerio) model. Mycotoxin exposures were carried out at five concentrations (0.0064, 0.064, 0.64, 6.4, and 64 μM). Morphological and photomotor screenings were conducted at 24 hours...
An experiment was designed to simulate field conditions of tansy
ragwort poisoning in cattle and horses.
Four calves and four ponies were fed pelleted feed containing 5%
Senecio jacobaea and two ponies and two calves were used as controls.
The feeding continued for two months. Following this, the chronic
delayed...
There have been many studies that describe the protective degradation or metabolism of potentially harmful plant toxins, such as, mimosine from Leucaena leuconcephala, pyrrolizidine alkaloids from tansy ragwort (Senecio jacobaea), oxalate and some mycotoxins by rumen microbes. There are many cases of plant-related toxicoses suffered by ruminant animals where there...
The anaerobic and highly reductive conditions found in the ovine rumen are considered favorable for the degradation of the nitroaromatic explosives such as hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX). In this study, we used stable-isotope-probing to determine the bacteria responsible for the degradation of RDX in the rumen. Results indicate 10 μg mL⁻¹ (45...
Metabolic defects within the different tissues and cell types of the eye give rise to many human ocular diseases. Polymorphisms in the Cytochrome P450 (CYP) family have been associated with many ocular disorders, particularly Cytochrome P450 1B1 (CYP1B1). Mutations in CYP1B1 have been linked to ocular diseases such as Primary...
Environmental contamination along roadways with lead from processed
petroleum and automotive residues has been reported. Toxicity to the herbivores grazing these areas has not been well studied. Comparison of lead concentrations adjacent to roads in Kuwait and in Oregon, USA was studied. Soil samples were taken from three sites at...