Bioelution assays are fast, simple alternatives to in vivo testing. In this study, the intra- and inter-laboratory variability in bioaccessibility data generated by bioelution tests were evaluated in synthetic fluids relevant to oral, inhalation, and dermal exposure. Using one defined protocol, five laboratories measured metal release from cobalt oxide, cobalt...
Light availability strongly influences stream primary production, water temperatures and resource availability at the base of stream food webs. In headwater streams, light is regulated primarily by the riparian forest, but few studies have evaluated the influence of riparian forest stand age and associated structural differences on light availability. In...
Infection with Helicobacter pylori is a major risk factor for the development of gastric cancer, and infection with strains carrying the virulence factor CagA significantly increases this risk. To investigate the mechanisms by which CagA promotes carcinogenesis, we generated transgenic zebrafish expressing CagA ubiquitously or in the anterior intestine. Transgenic...
Met is a prognostic indicator of colorectal cancer patient survival. Therapies that target Met may therefore have beneficial outcomes in the clinic. Recently, EGCG was reported to suppress Met activation, although the mechanisms were not elucidated. HCT116 and HT29 human colon cancer cells were used to examine the relationships between...
This report describes how energy is used in at the Hatfield Marine Science Center, and includes recommendations on cost effective steps that could be taken to reduce energy and waste costs. The contents are based on a recent visit to the facilities in Newport, Oregon.
The genome of a herpesvirus highly pathogenic to rabbits, leporid herpesvirus 4 (LHV-4), was analyzed using high-throughput DNA sequencing technology and primer walking. The assembled DNA sequences were further verified by restriction endonuclease digestion and Southern blot analyses. The total length of the LHV-4 genome was determined to be about...
Purpose of the Study:
The purpose of the study was to determine the characteristics
of existing secondary school advisory committees and the effects
that these groups have on local vocational programs which they
serve. The major purpose of this study was to ascertain, through
statistical analyses, the degree to which...
Conventional soil maps represent a valuable source of information about soil
characteristics, however they are subjective, very expensive, and time-consuming to
prepare. Also, they do not include explicit information about the conceptual mental
model used in developing them nor information about their accuracy, in addition to the
error associated with...