An important impact of the genome technology revolution will be the elucidation of mechanisms of cancer pathogenesis, leading to improvements in the diagnosis of cancer and the selection of cancer treatment. Integrated with current well-studied massive knowledge and findings about the role of protein-coding mutations in cancer, demystifying the functional...
Small business energy analysts often specialize in one aspect of the business. This specialized focus is done by necessity due to scarcity of resources and to maintain a proprietary market niche. However, this specialized focus results in a growth inhibitor due to their lack of ability to address all the...
Improving the understanding the relations of sustainability behaviors in manufacturing systems and actively engaging with manufacturers (especially SMEs) in sustainability efforts is key to the long-term success of U.S. industry and the natural environment. This study addresses this urgent need by establishing a systemic approach for the design of costing...
Simulated Annealing and Threshold Accepting are two stochastic search algorithms that have been successfully used on a variety of complex and difficult problem sets. Due to their stochastic nature they are not guaranteed to produce the same result for each run. This means that these techniques actually produce a distribution...
As the growth in demand for sustainable manufacturing continues, companies must begin to make conscious design decisions with regard to the sustainability of their products. This means balancing economics of production with environmental and social performance. Thus, design and manufacturing engineers must consider economic, environmental, and social aspects simultaneously when...
Auctions are used to solve resource allocation problem between many agents and many items in real-world settings. Unfortunately, in most cases, it is possible for selfish agents to manipulate the system for their own interest at the expense of the social welfare. Such manipulation can be prevented using the Vickrey-Clarke-Groves...
This study focused on the potential water and energy savings from implementing a revised schedule of a recirculation pump connected to a condensing gas tankless water heater located in a study home in Portland, Oregon. The existing recirculation pump activation schedule was studied for its impact on the overall water...
Physical activity recognition using accelerometer data is a rapidly emerging field with many real-world applications. Much of the previous work in this area has assumed that the accelerometer data has already been segmented into pure activities, and the activity recognition task has been to classify these segments. In reality, activity...
Air traffic flow management over the U.S. airpsace is a difficult problem. Current management approaches lead to hundreds of thousands of hours of delay, costing billions of dollars annually. Weather and airport conditions may instigate this delay, but routing decisions balancing delay with congestion contribute significantly to the propagation of...
In high volume automated discrete item batch production systems, the batches or lots are typically fixed quantity (i.e., size), with setups incurred between the different production lots. Processing times for the fixed-size lots are relatively constant when the workstation is operating however, random workstation disruptions cause variability in the lot...