Clostridium perfringens type A isolates produce the spore-specific enterotoxin, CPE, upon sporulation in the gastrointestinal tract of humans and animals. Spo0A is a response regulator representing the major transcription factor for sporulation initiation in C. perfringens. In Bacillus subtilis, a multicomponent phosphorelay involving five histidine kinases (KinA-KinE), the intermediate response...
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Acknowledgments
The Sarker Lab:
Dr. Mahfuzur Sarker
I-hsiu Huang
Dr. Deepa Raju
DanielParedes-Sabja
Nahid
About 48 million cases of Foodborne illnesses (FBIs) are estimated to occur every year in the US. These are diseases caused by contamination of foods with bacteria, viruses, protozoa, parasites and toxic chemicals. Clostridium difficile infections (CDIs) are an important health-care and community associated problem. Since C. difficile spores have...
Clostridium perfringens is the causative agent of gas gangrene and the 3rd most common cause of type A food borne disease in the United States. Critical to the pathogenicity of C. perfringens is the ability of this bacterium to produce highly resistant, metabolically dormant spores that can resume metabolic function...
Vibrio parahaemolyticus is a foodborne pathogen recognized as the leading cause of acute gastroenteritis associated with consumption of raw and undercooked seafood, particularly raw oysters, with major symptoms of nausea, vomiting, abdominal cramps and diarrhea. It is estimated that 45,000 cases of V. parahaemolyticus infection occur each year in the...
Clostridium perfringens type A isolates producing enterotoxin (CPE) are an
important cause of both food poisoning (FP) and non food borne gastrointestinal
diseases (NFBGID) in both humans and animals. C. perfringens type A food
poisoning is caused by isolates carrying the CPE encoding gene (cpe) on the
chromosome while the...
Clostridium perfringens type A isolates, an anaerobic enterotoxigenic spore forming bacterium, are the third leading cause of food-borne disease in the United States. Factors that contribute to the virulence of C. perfringens include the ability of the bacterium to form heat resistant spores and to produce an enterotoxin (CPE). Although...
This thesis synthesizes surficial structural data, a detailed analysis of an earthquake in 1944, and historical seismicity into a new model of crustal scale deformation in the eastern Precordillera in northwestern Argentina in the vicinity of San Juan. The eastern Precordillera was uplifted during previous thin-skinned deformation episodes, and is...
Understanding which factors motivate farmers to adopt certain practices is an important part of helping to solve many agri-environmental issues. This study uses 19 interviews with farmers along Oregon’s Willamette River, a statewide producer survey, and select interviews with organizations and agencies active in the farming community to examine the...