Injection of a 2.0 mg Cd
²⁺
/kg B.W. (I.P. as CdC1
₂
in
.05 M NaAc, pH = 6.9-7.2, .15 M or p = .15 with NaCl) resulted
in a decrease in ceruloplasmin (EC 1.12.3) p-phenylenediamine
oxidase activity within one hour of injection.
Maximal decrease (40%) occurred within six...
Selenium deficiency in rats results in increased carbon metabolism,
approaching twice the rate of selenium supplemented animals
(normal). This is also reflected in a 50 percent increase in lysosomal
enzyme activity in tissues of selenium deficient animals.
Isolation of rat liver lysosomes shows a 17 percent increase in
membrane thickness...
An in vitro study was conducted to investigate the metabolism and distribution of Se⁷⁵-selenite and Se⁷⁵-selenomethionine (SEM) in
chick blood. Se⁷⁵-selenite is taken up by RBC (13% within 20
minutes) and expelled into the plasma to become bound to proteins. In
contrast, Se⁷⁵-SEM showed a more gradual and continuous buildup...
Studies were conducted to investigate the metabolism of
selenium (Se) , and the influences of Se on the metabolism of cadmium (Cd) and inorganic mercury (Hg) in rats, and in ram semen in
vitro. Se-deficient (-Se) or Se-adequate (+Se) rats were injected intraperitoneally with either ¹⁰⁹CdCl₂ (5 μCi/rat) or ²⁰³HgN0₃...
The objective of our study was to investigate the effect of selenium on
selenoprotein W. Western blot analysis indicated that selenoprotein W is present in
muscle, brain, testis and spleen of rat tissues. Tissue distribution of selenoprotein W
was not altered in rats fed various selenium levels. Among muscle, brain,...
The objective of this study was to further determine the distribution of
selenoprotein W (SeW) in tissues from rats and sheep fed different selenium levels and to
search for the possible functions of this protein. In the rat study a total of 28 rat tissues
were examined and SeW was...