Ice cores are considered the gold standard for recording past climate and biogeochemical changes. However, gas records derived from ice core analysis have until now been largely limited to centennial and longer timescales because sufficient temporal resolution and analytical precision have been lacking, except during rare times when atmospheric concentrations...
Xanthohumol, a prenylated flavonoid found in hops and beer, possesses a long-standing reputation to improve health. Xanthohumol’s cytotoxicity to a wide variety of cancer cell lines is well-established. Herein we provide further insight into the cytotoxicity of not only xanthohumol, but also its non-estrogenic derivatives, to a number of colonic...
Studies were conducted to determine the influence of formulation and molecular configuration of some chlorinated-phenoxyalkylcarboxylic acid herbicides on their absorption, translocation and metabolism in bigleaf maple, Acer macrophyllum, Pursh. Five to eight year old bigleaf maple seedlings were treated with one percent solutions of carbon 14-labeled herbicids. After three days...
People with intellectual and developmental disabilities (IDD) engage in lesser physical activity (PA) and more time in sedentary activities as compared to those without disabilities. A subset of people with IDD who are most vulnerable to develop habits detrimental to health is the emerging adults who are transitioning from adolescence...
Mitotic recombination is a common autosomal mutation in mammalian cells involving crossover events between homologous chromosomes. This process can convert a cell with a heterozygous deficiency to one with a homozygous deficiency, and thus often represents the second step in tumor suppressor gene inactivation. In this study I examined the...
The multistage model of carcinogenesis states that an accumulation of mutations in genes that are important for maintaining cellular homeostasis may lead to cancer. A specific type of mutation observed in particular types of cancer is the CC-->TT mutation found in the TP53 gene of patients with basal or squamous...
DNA damage, if not repaired, can become a mutation. Mutation
accumulation is associated with initiation and progression of tumorigenesis. DNA
mismatch repair (MMR) is required for maintaining genetic stability by repairing
replication errors. Biochemical studies have shown that MMR also recognizes
mismatch-causing DNA lesions, suggesting the role of MMR in...
A decline in the oxygen cost of exercise enhances exercise tolerance and performance. Substantial research has shown that dietary nitrate lowers the oxygen cost of exercise in sedentary humans; however, the metabolic determinants regarding how dietary nitrate influences oxygen consumption in skeletal muscle is not known. We addressed this gap...
The Western Lake Survey (WLS) of 1985 documented the status of lake water chemistry across the western US and inferred population representations of various subregions and geomorphic units via statistically analyses. Results from this 1985 study indicated that lakes of the Oregon Cascades had the second most pristine and dilute...
Reinforced concrete (RC) column-footing substructures are widely used to support bridges along critical transportation corridors in Oregon. Those built prior to 1971 were typically designed to resist only gravity loads. Therefore, they are vulnerable to damage or collapse during strong ground shaking. To prevent collapse, seismic retrofits have been developed...
Earth’s atmosphere is unequivocally warming due to CO₂ and other greenhouse gas (GHG) emissions from human activities and this is having widespread impacts on forest ecosystems that provide important services to human societies. Forest ecosystems help regulate atmospheric CO2 concentrations by sequestering carbon in tree biomass and soils, which is...
Atomic Layer Deposition (ALD) is a promising technique for the production of
biologically safe, wear resistant and corrosion protective coatings for orthopedic
applications. In this work, the impact of coating thickness and surface preparation on the
hardness (H), elastic modulus (E), wear resistance, and delamination of ALD Al2O3 films
is...
Many failures of interpersonal communication and coordination in the aircraft cockpit have been found to occur as a result of poor management of flightdeck 'resources'. Crew Resource Management (CRM) is a concept that has evolved within the aviation community to specifically address this issue of resource management. The concept of...
Interpretation of ice core trace gas records depends on an accurate understanding of the
processes that smooth the atmospheric signal in the firn. Much work has been done to understand the
processes affecting air transport in the open pores of the firn, but a paucity of data from air trapped...
Full Text:
trapping in
polar firn
Mitchell, L. E., Buizert, C., Brook, E. J., Breton, D. J., Fegyveresi, J
We present a new high-precision, high-resolution record of atmospheric methane from the West Antarctic Ice Sheet (WAIS) Divide ice core covering 1000–1800 C.E., a time period known as the late preindustrial Holocene (LPIH). The results are consistent with previous measurements from the Law Dome ice core, the only other high-resolution...
The origin of the late pre-industrial Holocene (LPIH) increase in atmospheric methane concentrations has been much debated. Hypotheses invoking changes in solely anthropogenic sources or solely natural sources have been proposed to explain the increase in concentrations. Here two high-resolution, high-precision ice core methane concentration records from Greenland and Antarctica...
Full Text:
the
Atmospheric Methane Budget
Authors: Logan Mitchell1*, Ed Brook1, James E. Lee1, Christo
Interpretation of ice core trace gas records depends on an accurate understanding of the
processes that smooth the atmospheric signal in the firn. Much work has been done to understand the
processes affecting air transport in the open pores of the firn, but a paucity of data from air trapped...
Full Text:
influence of layering on bubble trapping in polar firn
LoganE. Mitchell1,2,*, Christo Buizert1, Edward
The origin of the late pre-industrial Holocene (LPIH) increase in atmospheric methane concentrations has been much debated. Hypotheses invoking changes in solely anthropogenic sources or solely natural sources have been proposed to explain the increase in concentrations. Here two high-resolution, high-precision ice core methane concentration records from Greenland and Antarctica...
Full Text:
Anthropogenic Contribution to the
Atmospheric Methane Budget
LoganMitchell,* Ed Brook, James E. Lee, Christo
The origin of the late pre-industrial Holocene (LPIH) increase in atmospheric methane concentrations has been much debated. Hypotheses invoking changes in solely anthropogenic sources or solely natural sources have been proposed to explain the increase in concentrations. Here two high-resolution, high-precision ice core methane concentration records from Greenland and Antarctica...
Physical activity is associated with significant health benefits. These benefits include lower risk of cardiac disease, depression, and obesity. Physical activity in young children, 1-5 years old, is extremely important as children need to develop foundations of physical activity in order promote lower risk for diseases. A study with nine...
Physical activity is important for young children with and without disabilities. However, recent investigations have found that young children with and without disabilities spend less time in physical activity than is recommended. Family and music factors have been shown to positively affect physical activity of this population in previous studies....
Children with disabilities report some of the lowest physical activity (PA) levels among U.S. children. Estimating the magnitude of PA disparities has been previously challenged by underreporting and variability in subsampling of children with disabilities. The present research leverages the redesigned National Survey of Children’s Health to estimate population-level disparities...
Three experiments were conducted to evaluate the various
methods and application rates of ferrous sulfate-heptahydrate in
the control of atmospheric ammonia in an enclosed broiler house.
The first experiment was conducted to determine the optimal
rate of application of ferrous sulfate-heptahydrate on built-up
litter. Ferrous sulfate was applied on built-up...
The 1980 eruptions of Mount St. Helens damaged or destroyed vegetation on more than 66,100 hectares (270,000 acres) within the Gifford Pinchot National Forest. The effects of the eruption on planting sites and seedling performance were unknown. Regeneration of "cut over" lands near Mount St. Helens has historically been limited...
The purpose of this paper was to consider whether the integration of
complementary and alternative medicine within coordinated care organizations would be
possible and beneficial. Per capita health expenditures in the Unites States are greater
than any other nation’s in the world. However, many complain that the organization and
distribution...
The thesis area covers 165 square miles including the greater
part of the northeastern quarter of the Mitchell quadrangle in north-central Oregon. The three stratigraphic units exposed in the area
consist of a variety of Tertiary volcanic rocks including the Clarno
Formation, the John Day Formation, and the Columbia River...
Nearly 9,000 feet of Cretaceous mudstones, shales, sandstone,
and conglomerates are exposed along the northeast-trending Mitchell
anticline of central Oregon, These rocks are divided into two formations
on the basis of criteria developed in this investigation. The
lower formation, hereby designated the Meyers Formation, is 4,716
feet thick at its...
Using robot motivation to see effects on modified ride-on car interaction has not yet been explored. Previous research has looked at the use of robots to encourage/motivate children (Bharatharaj et al., 2017; Conti et al., 2017; Johnson, 2003) and the benefits of using modified ride-on cars have also been previously...
The purpose of this study was to determine the viability of a mobile socially assistive robot (SAR) in a children’s free play environment. The researchers hypothesized that the SAR would prompt more movement among the participants. In order to test this, the researchers utilized a matched pair study in which...
Modified ride-on cars are used by young children with disabilities for self-directed mobility. Purpose: The purpose of this study is to (1) determine the association between modified ride-on car driving time, family income, and primary caregiver education level; and (2) compare modified ride-on car driving time, family income, and primary...
Modified ride-on cars (ROCs) offer children with disabilities access to independent mobility. Aims: 1) To examine the association between caregiver attitudes towards self-directed mobility, caregiver alignment with the medical and social models of disability, and total modified ROC driving time; 2) To compare caregiver attitudes towards self-directed mobility, caregiver alignment...
While the use of powered mobility devices for young children with mobility challenges has taken off in recent years following evidence that the use of powered mobility at a young age augments other traditional mobility skill interventions, the research is still limited and focuses on physical impacts more. Recently, the...
Purpose: The purposes of this study are to determine the within subject and between subject effects of play markings, gross motor toys, and a larger play space on the physical activity of children with and without disabilities. Method: A group comparison design was implemented and a total of 12 children...
This thesis describes the implementation of ultrasonic sensors to trigger a stimulus to increase peer interaction for children with disabilities using modified ride-on-cars for mobility. Modified ride-on-car technology has improved mobility for children with disabilities by effectively replicating the social benefits of a powered mobility device, yet there are opportunities...
In this study, I investigate how target value uncertainty may lead to acquirer mispricing of an acquisition target and how the mispricing may be a determinant of goodwill impairment. To the extent the mispricing leads to both high and low industry-adjusted purchase price multiples (PPMs are my proxies for overpayment...
Purpose: The purpose of this study is to determine the feasibility for an infant with Down syndrome to use a modified ride-on car that encourages the physical skills of pulling from sit-to-stand and standing with assistance. Method: An 8 month old boy, Child B, was video recorded during the 11...
The purpose of this study was to investigate the influence of alcohol
on freshman women during the critical transition into college.
Specifically, the study focused on differences in knowledge of alcohol
facts and attitudes toward use of alcohol among freshman women prior to
college. Further, the study focused on changes...
We report a decadally resolved record of atmospheric CO₂ concentration for the last 1000 years, obtained from the West Antarctic Ice Sheet (WAIS) Divide shallow ice core. The most prominent feature of the pre-industrial period is a rapid ∼7 ppm decrease of CO₂ in a span of ∼20–50 years at...
Individuals who have been traumatized have the opportunity to experience posttraumatic growth, conceptualized as positive changes that result from navigating highly challenging life circumstances (Tedeschi & Calhoun, 2004). The current model of posttraumatic growth (Calhoun, Cann, & Tedeschi, 2010) is based solely on cognitive-emotional processing yet by examining the role...
Horizontal ice-core sites, where ancient ice is exposed at the glacier surface, offer unique opportunities for paleo-studies of trace components requiring large sample volumes. Following previous work at the Pâkitsoq ice margin in West Greenland, we use a combination of geochemical parameters measured in the ice matrix (δ¹⁸O[subscript ice]) and...
Coral reef health has been in severe decline around the globe in the past several
decades, in many cases due to direct human impact. Human action, such as overfishing,
habitat destruction and nutrient loading, has caused coral coverage to drop to record lows,
threatening the future of these critically important...
DNA microarray technology is a powerful tool for analyzing patterns in gene expression data for thousands of genes. Due to a number of systematic variations in microarray experiments, the raw gene expression data is often obfuscated by undesirable technical noises. Various normalization techniques were designed in an attempt to remove...
Current neutron dosimetry methods rely on the assumption that charged particle equilibrium (CPE) is established within the tissue medium. This maintains that the kinetic energy transferred to the medium (KERMA) is equivalent to absorbed dose. However, this assumption is only valid for large volumes such as the whole body. For...
In this work we present a multiagent Fleet Coordination Problem (FCP). In this formulation, agents seek to minimize the fuel consumed to complete all deliveries while maintaining acceptable on-time delivery performance. Individual vehicles must both (i) bid on the rights to deliver a load of goods from origin to destination...
Nurseries are an important part of the agriculture industry of the United States. The nursery industry provides ornamental, forest, restoration and specialty products to many markets in N. America. The disease sudden oak death, caused by Phytophthora ramorum, has devastating environmental and economic impacts on forested land, the urban-forest interface,...
The research presented in this thesis is a continuation of collaboration between Oregon State University and Auburn University studying the feasibility of passively pumping liquid during boiling in a preferential direction using meso-scaled asymmetric surface patterns. Such a passive phase-change mechanism has great potential for thermal management in spacecraft and...
Drought represents an import part of natural hydrologic cycles that govern the rate and transportation of water on global and regional scales. (Trenberth, et al. 2015) Agriculturally, drought represents a threat to crop production and can endanger political and economic stability through the loss of resources and the threat of...
Cooperative multiagent systems are used as solution concepts in many application domains including air traffic control, satellite communications, and extra planetary exploration. As systems become more distributed and complex, we observe three phenomena. First, these systems cannot be accurately modeled, rendering traditional model based control methods inadequate. Second, system parameters...
Reclaimed water is a key source in overall global water management and sustainability;
however, small concentrations of antibiotics in treated wastewater effluent threaten
induction of antibiotic resistance in naturally-occurring soil bacteria and pathogens in
irrigated soils. This type of chronic exposure has the potential to lead to more severe food...
When Charles Guiteau killed U.S. President James Garfield, he claimed that God had ordered him to do so. During his trial, Guiteau’s lawyers plead not guilty by reason of insanity, and the question of Guiteau’s innocence or guilt quickly became a question about the very nature of insanity itself. In...
Humpback whale populations in Antarctica are recovering after intensecommercial whaling in the 20th century. Along the Western Antarctic Peninsula (WAP)this recovery is occurring in an environment that is experiencing the fastest warming ofany region on the planet. To begin to understand the dynamics of this recovery undersuch dramatic climate change,...
We explore the possibility of estimating sparse inverse covariance matrices when for scientific reasons the covariance matrix is restricted to be a non-negative matrix. The process mirrors the graphical lasso process developed by Friedman and others(2008) that did not have this additional constraint.Accordingly, the Lasso procedure is done through coordinate...
Upper Klamath Lake in southern Oregon has two species of lacustrine suckers,
Lost River sucker Deltistes luxatus and shortnose sucker Chasmistes brevirostris that
were historically abundant. Results of surveys performed in the mid-1980's indicated that populations of both species were declining and ageing with apparent recruitment failure in most years...
Nuclear fusion reactors comprise a significant field of study due to their potential to provide a limitless, clean, and sustainable source of energy. The inertial electrostatic confinement fusor is a type of fusion-generating device that accelerates deuterium gas to the conditions required for fusion. The goal of this research was...
Rates of sediment transport were determined using tracer gravel and a RFID antenna array at Oak Creek (Oregon) to compare a new method with an existing transport relation created from data previously collected in the same study reach. Close to 3,000 tracers were deployed throughout the study reach and were...
The Genome-Wide Association Studies approach was used to detect Quantitative Trait Loci associated with tocochromanol concentrations using a panel of 1,466 barley accessions. All major tocochromanol types- α-, β-, δ-, γ-tocopherol and tocotrienol- were assayed. We found 13 single nucleotide polymorphisms associated with the concentration of one or more of...
Human satiety and hunger are usually measured by observations of
eating behavior or by verbal reports. Neither of these seems to be an
objective method of measurement. Some studies have indicated that pupil
responses to pictures of food may correspond with interest in food. The
objective of this study was...
The Clarno Formation is a series of volcanic, volcaniclastic, and related intrusive rocks located in central Oregon. It is the westernmost extent of a broader Eocene magmatic belt that covers much the western United States. The magmatic belt stretches eastward from Oregon to western South Dakota, and from the Canadian...
Two experiments examined the dynamic interaction between cognitive resources in short-term memory and bimanual object manipulation by extending recent research by Logan and Fischman (2011). In Experiment 1, 16 participants completed a bimanual end-state comfort task and a memory task requiring serial recall of 12 words or pictures. The end-state...
Executive function (EF) is an extensively researched topic as a predictor for academic achievements for children. Delineated as qualities of self-regulation, EF prepares a child to produce successful behaviors for their learning and social environments. Entering school with sufficient self-regulation skills is proven advantageous for scholarly performance. Within the early...
Childhood tooth decay is a prevalent and concerning public health issue that is often misunderstood or dismissed. In Oregon specifically, over 50% of children have experienced at least one instance of tooth decay and these rates are even higher for marginalized communities such as children living in poverty, children of...
Bicyclist safety at urban intersections is a critical element for encouraging an increase in bicycle commuting. With bicycle injury and fatality rates rising due to collisions with vehicles at signalized intersections, increasing the safety of riders continues to be an important consideration when promoting this mode of transportation. Previous research...
Fault zones are potential paths for release of radioactive nuclides from radioactive-waste repositories in granitic rock. This research considers detailed maps of en echelon fault zones at two sites in southern Sweden, as a basis for analyses of how their internal geometry can influence groundwater flow and transport of radioactive...
Neurofibromatosis Type 2 (NF2) is a genetic tumor disorder caused by mutations that inactivate the gene coding for the Merlin tumor suppressor. Patients with NF2 develop multiple tumors throughout the nervous system, mainly schwannomas, for which there is no cure or effective treatment. In NF2, redox signaling and oxidative stress...
Increased physical activity (PA) in children has been linked to improved quality of life, as well as the establishment of life-long PA habits that lead to improved health outcomes. The literature suggests that children who participate in organized sport programs engage in more PA than children who do not. Notably,...
Adapted physical activity and education (APA/APE) service-learning has received considerable attention as a training tool to prepare undergraduate students, including preservice physical education teachers, to work with people with disabilities (Hodge, 1998; Rowe & Stutts, 1987; Taliaferro et al., 2015). Much of this research focuses on demonstrating the effects of...
The possibility of synthesizing 1, 8-naphthyridines by the Doebner reaction has appeared in many reports. The method involves the introduction of electron releasing groups in the 6-position of 2-amino pyridine to activate the C-3 position. Previously Lewis used 6-methyl-2-amino pyridine with benzaldehyde and pyruvic acid, in an attempt to prepare...
Children with developmental disabilities (DDs) have been observed to have delays in motor skills compared to their age-matched peers without disabilities. Empirical research suggests that children with motor skill delays experience more internalizing and externalizing behaviours and that early motor skill difficulties may be an important indicator of future increases...
1-(2-pyridyl)-3-methyl-3-butene-2-ol was prepared by allowing 2-picolyllithium to react with methacrolein.
In the reaction of picolyllithium with crotonaldehyde, two products 1-(2-pyridyl)-4-methyl-3-butene-2-ol and 1-(2-pyridyl)-4-methyl-2-butene-4-ol were formed.
1-(2-pyridyl)-3-methyl-3-butene-2-ol was subjected to the low
pressure hydrogenation, using methanol as solvent and PtO₂ as catalyst. A red yellow liquid 1-(2-pyridyl)-3-methyl-2-butanol was
obtained. Derivatives of the...
Purpose: Children with Down syndrome (DS) may have limited opportunities to engage in independent mobility at the same age as their typically developing peers due to motor delays. The primary purpose of this study was to examine two activity-oriented outcomes - (1) onset of independent driving, and (2) onset of...
Two lots of six White Leghorn male chickens were fed diets containing
7.3% linoleic acid and either .075% ethoxyquin (lot 1) or 32.4
mg/kg of added vitamin E (lot II) for 47 weeks both of which were
designated as positive controls. A third group (lot III) containing 30
males received...