Background: Recent mapping of eukaryotic transcriptomes and spliceomes using massively parallel RNA sequencing (RNA-seq) has revealed that the extent of alternative splicing has been considerably underestimated. Evidence also suggests that many pre-mRNAs undergo unproductive alternative splicing resulting in incorporation of in-frame premature termination codons (PTCs). The destinies and potential functions...
Background:
Identifying cis-regulatory elements is critical in understanding the direct and indirect regulatory mechanisms of gene expression. Current approaches include DNase-seq, a technique that combines sensitivity to the nonspecific endonuclease DNase I with high throughput sequencing to identify regions of regulatory DNA on a genome-wide scale. While this method was...
In 1964, Zarantonello published a constructive method for
the solution of certain nonlinear problems in a Hilbert space. We
extend the method in various directions including a generalization
to a Banach space setting. A revealing geometric interpretation of
the method yields guidelines for the analysis.
BACKGROUND: Circadian clocks provide an adaptive advantage through anticipation of daily and seasonal environmental
changes. In plants, the central clock oscillator is regulated by several interlocking feedback loops. It was shown that a
substantial proportion of the Arabidopsis genome cycles with phases of peak expression covering the entire day.
Synchronized...
Full Text:
and cis-Regulatory Modules
SergeiA. Filichkin1, Ghislain Breton2¤a, Henry D. Priest1, Palitha
BACKGROUND: Circadian clocks provide an adaptive advantage through anticipation of daily and seasonal environmental
changes. In plants, the central clock oscillator is regulated by several interlocking feedback loops. It was shown that a
substantial proportion of the Arabidopsis genome cycles with phases of peak expression covering the entire day.
Synchronized...
BACKGROUND: Circadian clocks provide an adaptive advantage through anticipation of daily and seasonal environmental
changes. In plants, the central clock oscillator is regulated by several interlocking feedback loops. It was shown that a
substantial proportion of the Arabidopsis genome cycles with phases of peak expression covering the entire day.
Synchronized...
Plants possess two myosin classes, VIII and XI. The myosins XI are implicated in organelle transport, filamentous actin
organization, and cell and plant growth. Due to the large size of myosin gene families, knowledge of these molecular motors
remains patchy. Using deep transcriptome sequencing and bioinformatics, we systematically investigated myosin...
Full Text:
, SergeiA. Filichkin, Samuel E. Fox, Pankaj Jaiswal, Kira S. Makarova,
Eugene V. Koonin, and Valerian V
Plants possess two myosin classes, VIII and XI. The myosins XI are implicated in organelle transport, filamentous actin
organization, and cell and plant growth. Due to the large size of myosin gene families, knowledge of these molecular motors
remains patchy. Using deep transcriptome sequencing and bioinformatics, we systematically investigated myosin...
Plants possess two myosin classes, VIII and XI. The myosins XI are implicated in organelle transport, filamentous actin
organization, and cell and plant growth. Due to the large size of myosin gene families, knowledge of these molecular motors
remains patchy. Using deep transcriptome sequencing and bioinformatics, we systematically investigated myosin...
G. F. Drukarev has given a method for solving the Fredholm
equations which arise in the study of collisions between electrons
and atoms. He transforms the Fredholm equations into Volterra
equations plus finite algebraic systems. H. Brysk observes that
Drukarev's method applies generally to a Fredholm integral equation
(I-λ G)u...
One-electron oxidation of the μ-oxo dimer
(cis,cis-[Ruᴵᴵᴵ(bpy)₂(OH₂)]₂O⁴⁺, {3,3}) to {3,4} by S₂O₈²⁻ can
be described by three concurrent reaction pathways corresponding
to the three protic forms of {3,3}. Free energy
correlations of the rate constants, transient species dynamics
determined by pulse radiolysis, and medium and temperature
dependencies of the alkaline...
Full Text:
(bpy)2(OH2)]2O4+ “Blue Dimer”
James K. Hurst,† Margo Roemeling,‡ and Sergei V. Lymar
One-electron oxidation of the μ-oxo dimer
(cis,cis-[Ruᴵᴵᴵ(bpy)₂(OH₂)]₂O⁴⁺, {3,3}) to {3,4} by S₂O₈²⁻ can
be described by three concurrent reaction pathways corresponding
to the three protic forms of {3,3}. Free energy
correlations of the rate constants, transient species dynamics
determined by pulse radiolysis, and medium and temperature
dependencies of the alkaline...
Full Text:
-[Ru(bpy)2(OH2)]2O
4+ “Blue Dimer”
James K. Hurst,† Margo D. Roemeling,‡ and Sergei V. Lymar
One-electron oxidation of the μ-oxo dimer
(cis,cis-[Ruᴵᴵᴵ(bpy)₂(OH₂)]₂O⁴⁺, {3,3}) to {3,4} by S₂O₈²⁻ can
be described by three concurrent reaction pathways corresponding
to the three protic forms of {3,3}. Free energy
correlations of the rate constants, transient species dynamics
determined by pulse radiolysis, and medium and temperature
dependencies of the alkaline...
Facultative/winter six-row malting barley is a distinct elite germplasm pool and a valuable resource that may prove useful in meeting the challenges of climate change. To preserve its diversity and make it accessible to the research and agricultural communities, the Oregon State University and University of Minnesota barley breeding programs...
New seafloor mapping and sampling demonstrates that the eruption of the high-Ca boninites is clearly associated with rifting of the northern Tonga ridge and the northern Lau Basin at the northern termination of the Tonga Trench. There is very strong evidence for OIB plume related mantle sources involved in the...
We report new geochemical data for boninites and backarc basin-type basalts recovered from the northern termination of the Tonga trench and Lau Basin. Boninitic pillow lavas, ranging from high-Mg compositions to andesites and dacites, have been erupted within large submarine volcanic edifices (calderas and volcanoes) associated with active rifting of...
Barley (Hordeum vulgare) is an important component of heart-healthy
whole grain diets because it contains β-glucan. All current US barley
varieties with high β-glucan are spring habit and have waxy starch. Winter
varieties have agronomic advantages but require low-temperature tolerance
(LTT). Vernalization sensitivity (VS) is associated with higher
levels of...
Full Text:
. Cereal Chem. 79, 596—599.
Cuesta-Marcos, A., P. Szucs, T. J. Close, T. Filichkin, G. J. Muehlbauer,
K. P
Barley (Hordeum vulgare) is an important component of heart-healthy
whole grain diets because it contains β-glucan. All current US barley
varieties with high β-glucan are spring habit and have waxy starch. Winter
varieties have agronomic advantages but require low-temperature tolerance
(LTT). Vernalization sensitivity (VS) is associated with higher
levels of...
Barley (Hordeum vulgare) is an important component of heart-healthy whole grain diets because it contains β-glucan. All current US barley varieties with high β-glucan are spring habit and have waxy starch. Winter varieties have agronomic advantages but require low-temperature tolerance (LTT). Vernalization sensitivity (VS) is associated with higher levels of...