Platelets undergo morphological changes essential to hemostasis upon activation at sites of vascular injury. The Rho GTPases Rac1, Cdc42, and RhoA drive these changes. Rho guanine nucleotide dissociation inhibitors (RhoGDIs) bind to the Rho GTPases to block the GDP from dissociating from the Rho GTPases, as well as anchoring the...
The North Atlantic zone of Costa Rica is an alluvial plain, whose fairly good soils and warm, extremely wet climate generate serious weed problems in cultivated crops and pastureland. Basic foods - corn, beans, rice and yuca - are important small farm crops. New land is still being opened for...
The illicit use of opioids among young adults (18–25) has resulted in an increase of clients needing substance abuse treatment. Treatment programs are struggling to keep up with the influx of these young adults. Traditional models of care have some impact; however, there are not enough treatment centers that can...
Through improved adherence, once-monthly injectable extended-release naltrexone (XR-NTX)
may provide an advantage over other oral agents approved for alcohol and opioid dependence
treatment. The objective of this study was to evaluate cost and utilization outcomes between
XR-NTX and other pharmacotherapies for treatment of alcohol and opioid dependence.
Published studies were...
Major emphasis of this research study involved the evaluation
of nutrient transport by overland flow. Samples gathered at various
distances relative to a swine-waste spray irrigation system were
used for the nutrient evaluation.
As a result of this study, the following conclusions are made:
1. It is improbable that the...
Tetracycline (Tet)-resistant strains of Chlamydia suis were isolated from swine
farms in the Midwest. The isolation of the resistant strains was significant
because Tet is an antibiotic used to treat infections by veterinarians and
doctors. One of the tetracycline (Tet)-resistant strains, R19, was able to
survive in Tet up to...
Use of basalt aquifers for aquifer storage and recovery (ASR) systems is increasing in the Pacific Northwest due to the large aerial extent of the Columbia River Basalt Group and the suitability of basalts as ASR reservoirs. However, the degradation of trihalomethanes (THMs), potentially carcinogenic disinfection by-products present in the...
This study examines the relation between political parties in the United States and foreign direct investment (FDI) using a panel data gravity model of 42 countries from 1980 to 2006. The Democratic Party and the Republican Party differ on economic platforms, and the changing of relative power in government between...
Methane is the most abundant organic chemical in the
earth's atmosphere. Its abundance in the atmosphere is
increasing with time and has reached levels not seen in recent
geological history. The methane is produced both naturally, and
anthropogenically. One of the sources of anthropogenic methane
is manure from domesticated animals....
This thesis examines the recent history of the teaching of argument and its implications in the face of new writing standards being implemented in K-12 classrooms under the Common Core State Standards. The new educational policies will shift the focus of writing instruction onto argument writing as part of students'...
Currently, fungicide applications are the predominant method of control for the cool weather pathogen Microdochium patch (Microdochium nivale). Increasing pesticide restrictions have generated concern regarding management of Microdochium patch. Three separate field trials exploring non-traditional fungicides were conducted between 2013 and 2015 on an annual bluegrass (Poa annua L.) sand-based...
The structure and transcriptional activity of intranuclear
and isolated chromatin from logarithmically growing
yeast cells has been compared to chromatin from cells which
have entered the stationary phase and ceased growing. Both
chromatins show a similar nucleosomal repeat pattern and a
160 by repeat size when digested with staphlococcal nuclease....