The interaction of magma with continental crust at convergent margins is fundamental to
understanding if and how continents grow. Isotopic and elemental data constrain the
progressive stages of development of the magmatic underpinnings of the long-lived
Aucanquilcha Volcanic Cluster (AVC), situated atop the thick continental crust of the
central Andes...
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ABSTRACT OF THE DISSERTATION OF
Barry Alan Walker, Jr. for the degree of Doctor of Philosophy in
The interaction of magma with continental crust at convergent margins is fundamental to
understanding if and how continents grow. Isotopic and elemental data constrain the
progressive stages of development of the magmatic underpinnings of the long-lived
Aucanquilcha Volcanic Cluster (AVC), situated atop the thick continental crust of the
central Andes...
We report ³He/⁴He for 150 mid-ocean ridge basalt (MORB) glasses from the Southeast Indian
Ridge (SEIR). Between 81°E and 101°E ³He/⁴He varies from 7.5 to 10.2 R[subscript A], encompassing more than half the
MORB range away from ocean island hot spots. Abrupt transitions are present and in one case the...
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Helium isotopic textures in Earth’s upper mantle
David W. Graham1, BarryB. Hanan2, Christophe H�emond3
We report ³He/⁴He for 150 mid-ocean ridge basalt (MORB) glasses from the Southeast Indian
Ridge (SEIR). Between 81°E and 101°E ³He/⁴He varies from 7.5 to 10.2 R[subscript A], encompassing more than half the
MORB range away from ocean island hot spots. Abrupt transitions are present and in one case the...
As a persistent organic contaminant, perfluorooctanesulphonic acid (PFOS) has been widely detected in the environment, wildlife, and humans. The present study revealed that zebrafish embryos exposed to 16 µM PFOS during a sensitive window of 48-96 hour post-fertilization (hpf) disrupted larval morphology at 120 hpf. Malformed zebrafish larvae were characterized...
Background: Prenatal mercury (Hg) exposure is associated with adverse child neurobehavioral
outcomes. Because Hg can interfere with placental functioning and cross the placenta to target the
fetal brain, prenatal Hg exposure can inhibit fetal growth and development directly and indirectly.
Objectives: We examined potential associations between prenatal Hg exposure assessed...
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Neurobehavioral Outcomes
Jennifer Z.J. Maccani, Devin C. Koestler, Barry Lester, E. Andrés Houseman, David A
Background: Prenatal mercury (Hg) exposure is associated with adverse child neurobehavioral
outcomes. Because Hg can interfere with placental functioning and cross the placenta to target the
fetal brain, prenatal Hg exposure can inhibit fetal growth and development directly and indirectly.
Objectives: We examined potential associations between prenatal Hg exposure assessed...
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Jennifer Z.J. Maccani, Devin C. Koestler, Barry Lester, E. Andrés Houseman, David A.
Armstrong, Karl T
Background: Prenatal mercury (Hg) exposure is associated with adverse child neurobehavioral
outcomes. Because Hg can interfere with placental functioning and cross the placenta to target the
fetal brain, prenatal Hg exposure can inhibit fetal growth and development directly and indirectly.
Objectives: We examined potential associations between prenatal Hg exposure assessed...
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Mercury and
Adverse Neurobehavioral Outcomes
Maccani, J., Koestler, D. C., Lester, B., Houseman, E. A
Vitamin E improved liver histology in children and adults with NAFLD who participated in TONIC and PIVENS clinical trials,
but with significant inter-individual variability in its efficacy. Cytochrome P450 4F2 (CYP4F2) is the major enzyme
metabolizing Vit E, with two common genetic variants (V433M, rs2108622 and W12G, rs3093105) found to...
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Participated in PIVENS and TONIC Clinical Trials
Athinarayanan S, Wei R, Zhang M, Bai S, Traber MG, et al
As a persistent organic contaminant, perfluorooctanesulphonic acid (PFOS) has been widely detected in the environment, wildlife, and humans. The present study revealed that zebrafish embryos exposed to 16 µM PFOS during a sensitive window of 48-96 hour post-fertilization (hpf) disrupted larval morphology at 120 hpf. Malformed zebrafish larvae were characterized...
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zebrafish organogenesis
Chen, J., Tanguay, R. L., Tal, T. L., Gai, Z., Ma, X., Bai, C., ... & Dong, Q