Diet History Questionnaires (DHQ) can only provide general information about a person’s nutritional intake. It is unable to cluster groups of people based on diets or lifestyles, nor identify specific foods that may play a role in disease prevention. The aim of this study was to validate the use of...
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polyphenols can lower certain diseases.
Acknowledgements
Special thanks to Fred Stevens, JaewooChoi, Sandra
We hypothesized that vitamin E (α-tocopherol) is required by the developing embryonic brain to prevent depletion of highly polyunsaturated fatty acids, especially docosahexaenoic acid (DHA, 22:6), the loss of which we predicted would underlie abnormal morphological and behavioral outcomes. Therefore, we fed adult 5D zebrafish (Danio rerio) defined diets without...
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deficient zebrafish
(danio rerio) embryos
Melissa Q. McDougall a,b, JaewooChoi a, Jan F. Stevens a,c,f
Diet History Questionnaires (DHQ) can only provide general information about a person’s nutritional intake. It is unable to cluster groups of people based on diets or lifestyles, nor identify specific foods that may play a role in disease prevention. The aim of this study was to validate the use of...
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Crystal V. Carrillo1, Rachel Hahn1,2 , Jaewoo Choi2, Gerd Bobe1,2, and Jan F. Stevens Ph.D.2,3
1College of
The protein palmitoylation cycle has been shown to be important for protein signaling and synaptic plasticity. Data from our lab showed a change in the palmitoylation status of certain proteins with age. A greater percentage of the NMDA receptor subunits GluN2A and GluN2B, along with Fyn and PSD95 proteins, were...
We hypothesized that vitamin E (α-tocopherol) is required by the developing embryonic brain to prevent depletion of highly polyunsaturated fatty acids, especially docosahexaenoic acid (DHA, 22:6), the loss of which we predicted would underlie abnormal morphological and behavioral outcomes. Therefore, we fed adult 5D zebrafish (Danio rerio) defined diets without...
We hypothesized that vitamin E (α-tocopherol) is required by the developing embryonic brain to prevent depletion of highly polyunsaturated fatty acids, especially docosahexaenoic acid (DHA, 22:6), the loss of which we predicted would underlie abnormal morphological and behavioral outcomes. Therefore, we fed adult 5D zebrafish (Danio rerio) defined diets without...
To test the hypothesis that embryogenesis depends upon α-tocopherol (E) to protect embryo polyunsaturated fatty acids (PUFAs) from lipid peroxidation, new methodologies were applied to measure α-tocopherol and fatty acids in extracts from saponified zebrafish embryos. A solid phase extraction method was developed to separate the analyte classes, using a...
Metabolic syndrome, characterized by a collection of risk factors including abdominal obesity, insulin insensitivity, elevated plasma triglycerides, hypertension and low plasma high-density lipoproteins (HDLs), is a major contributing factor to the development of cardiovascular diseases and type II diabetes (T2D). Xanthohumol (XN), a flavonoid isolated from Humulus lupulus cones, has...
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repeated using C57BL/6J female mice
Acknowledgements
Fred Stevens
JaewooChoi
Ralph Reed
Val Miranda
Obesity is achieved at the point where fat accumulation begins to exert deleterious effects on an organism. The human body accrues fat when there is an energy imbalance occurring, where caloric intake exceeds expenditure.Many anti-obesity drugs used in the past have had undesirable side effects, and currently there is a...
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support our hypothesis
24
Acknowledgements
J.F. Stevens, Ph. D.
JaewooChoi, Ph. D.
Val Miranda, Ph. D
Obesity is achieved at the point where fat accumulation begins to exert deleterious effects on an organism. The human body accrues fat when there is an energy imbalance occurring, where caloric intake exceeds expenditure.Many anti-obesity drugs used in the past have had undesirable side effects, and currently there is a...
Full Text:
helping me with my cell culture
experiments. I am also deeply indebted to Dr. JaewooChoi for
helping