Global warming is expected to cause significant changes in the pattern of precipitation minus evaporation (𝑃 − 𝐸), which represents the net flux of water from the atmosphere to the surface or, equivalently, the convergence of moisture transport within the atmosphere. In most global climate model simulations, the pattern of...
Cell signaling under external stimulation is a critical mechanism that governs many biological processes such as cell proliferation, cell migration, and cell apoptosis, etc. For multicellular organisms, the ability to synchronize heterogeneous individual cellular responses through intercellular communication is crucial to maintain normal functionality. However, even though the biological pathways...
The continued long-term use of fossil fuels as a primary energy source has resulted in dramatic increases in greenhouse gas emissions and the associated concerns of climate change and environmental pollution. A key strategy to circumvent these issues is a global shift away from fossil fuels toward renewable energy sources....
Over time, Open Source Software (OSS) has become indispensable in the creation and upkeep of software products, serving as the fundamental building block for widely used solutions in our daily lives, including applications that enable communication, entertainment, and productivity. A sustainable OSS ecosystem is one that attracts and retains a...
In this dissertation, the primary objective is to discover more sustainable electrode materials and study new reaction mechanisms using aqueous electrolytes. The first study conducted reveals a reversible conversion reaction from copper to Cu2CO3(OH)2. The reaction mechanism uses OH- and CO32- as charge carriers at the cathode. The results open...
Coastal communities rely on the abundant ecosystem services derived from robust conservation areas in offshore marine waters (Campbell, 2019). United Nations member states support the Sustainable Development Goal (SDG) framework, wherein the 14th guideline asserts the importance of life under water. Protected marine environments are critical to the survival of...
Machine learning applied to computer architecture has rapidly transitioned from a theoretical novelty to being a driving force behind design, control, and simulation in practically all components. These machine-learning-based methodologies are further notable for their scalability to increasingly complex design challenges, which has allowed these methodologies to surpass the prior...
Interactions between proteins are essential to life, driving and regulating a majority of processes within all living cells. Study of protein-protein interactions reveals that some proteins act as hubs within networks of interactions, binding to many partner proteins. These hubs therefore are of particular importance to understanding protein function, interwoven...
Orthopaedic soft tissue degenerative diseases significantly affect the population, especially as it ages. Degeneration is characterized by a progressive loss of extracellular matrix (ECM) components necessary for the proper functioning of the tissues and joints, eventually leading to pain and dysfunction. In humans, the intervertebral disc (IVD) and tendon are...
This dissertation presents novel, field-activated smart material systems for the actuation and control of autonomous robots. Smart materials, a type of material whose properties can be changed with an external stimuli, represent a promising direction to expand upon existing robotic control and actuation methods, particularly in the sub-fields of soft...