Index Catalog // ScholarsArchive@OSU

Creator:: Goodale, Britton C.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous in the environment as components of fossil fuels and by-products of combustion. Defining toxicity mechanisms for this large family of multi-ring structures and substituted derivatives is a substantial challenge. Several PAHs, such as benzo(a)pyrene (BaP), are mutagenic, toxic to wildlife, and classified as probable...
Resource Type:: Dissertation
Full Text:: Developmental Toxicity of Polycyclic Aromatic Hydrocarbons

Creator:: Franzosa, Jill A.
Abstract:: microRNAs (miRNAs), ~21-24 nucleotide-long RNAs that post-transcriptionally regulate gene expression, have rapidly become one of the most extensively studied mechanisms of the past decade. Since their discovery as temporal regulators of post-embryonic development in C. elegans, miRNAs have been functionally implicated in almost every cellular process investigated to date. miRNAs...
Resource Type:: Dissertation
Full Text:: developmental stages. First, to uncover the potential role of miRNAs in teratogenicity, we investigated

Creator:: Nunes, Jason L.
Abstract:: The Polycomb group (PcG) of genes of Drosophila melanogaster Meigen are involved in developmental regulation through chromatin remodeling. Homologs of PcG genes have been identified in both plant and animal species. In this study, we detail the identification and characterization of Triticum enhancer of zeste 1 (Tez1), a homolog of...
Resource Type:: Masters Thesis
Full Text:: Polycomb group (PcG) of genes of Drosophila melanogasier Meigen are involved in developmental regulation

Creator:: Golonzhka, Olga
Abstract:: CTIP2 is a C2H2 zinc finger transcription factor that plays important yet poorly understood roles in mouse development. CTIP2 is known to be highly expressed in the central nervous system, skin and T lymphocytes during embryogenesis. CTIP2-null mice die perinatally of unknown causes and exhibit defects in multiple organ systems...
Resource Type:: Dissertation
Full Text:: play a central role in controlling the developmental processes. The genetic programs governed by

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