The WWC family consists of three proteins‐ KIBRA/WWC1, WWC2, and WWC3. The three proteins share a similar primary structure and interact with a common set of proteins. Each paralog contains two WW domains which recognize proline‐rich sequences of the type PPxY (P is proline, Y is tyrosine, x is any...
Davidson Seamount, a volcano located about 80 km off the central California coast, has a volume of
~320 km³ and consists of a series of parallel ridges serrated with steep cones. Davidson was sampled and
its morphology observed during 27 ROV Tiburon dives. During those dives, 286 samples of lava,...
Ultrafast spectroscopy has recently gained momentum as a powerful, noninvasive characterization toolset capable of studying a diverse array of samples with applications in chemistry, physics, biology, engineering, and more. Two popular ultrafast spectroscopic techniques include femtosecond transient absorption (fs-TA) and femtosecond stimulated Raman spectroscopy (FSRS). The latter of these techniques...
In the past decades, femtosecond stimulated Raman spectroscopy (FSRS) has been gaining tremendous popularity in fundamental sciences stemming from chemistry to biology. It is capable of capturing both equilibrium and non-equilibrium structural information across a broad range of timescales with simultaneously high temporal and spectral resolutions. Femtosecond transient absorption spectroscopy...
Ultrafast spectroscopy can exploit the structure-function relationship of chemical- and biological-based systems. More specifically, femtosecond stimulated Raman spectroscopy (FSRS) provides ground- and excited-state vibrational information with simultaneously high spectral (spatial) and temporal resolutions. The electronic counterpart, femtosecond transient absorption (fs-TA), complements FSRS data analysis as part of a comprehensive approach...
The goal of this study was to develop an understanding of the nature of surge wave loading on
wood framed residential structures for a variety of building configurations and test conditions.
The objectives of the study were: (1) to measure forces on a 1/6th scale wood framed
residential structure, (2)...
During the Canterbury Earthquake Sequence (CES) in Christchurch, NZ, an estimated $15B in damages occurred due to liquefaction-induced phenomena, illustrating the importance of understanding site-specific responses to seismic ground motions, as well the importance of accurately predicting liquefaction severity. One potential method for improving the understanding of how a site...
In this dissertation, excited state proton transfer (ESPT) and its inhibition in solution and protein environments are revealed using both femtosecond transient absorption (fs-TA) spectroscopy and femtosecond stimulated Raman spectroscopy (FSRS). Using a tunable Raman pump to enhance transient vibrational features of the photoacidic chromophore HPTS in methanol and methanol...