Causal inference is an important analytical tool to bridge the gap between prediction and decision-making. However, learning a causal network solely from data is a challenging task. In this work, various techniques have been explored for a better and improved causal network learning from data. Firstly, the problem of learning...
Ph.D. candidate Qi Wei's thesis consists of two projects: Chemotherapy Project: a study based on the research paper "Predicting chemotherapy response of various cancer types using a variational auto-encoder approach" submitted to the bioRxiv preprint archive and accepted by the BMC bioinformatics; and Wound Monitor Project: implementing and assessing analytics...
We describe a series of novel computational models, CERENKOV (Computational Elucidation of the REgulatory NonKOding Variome) and its successors CERENKOV2, CERENKOV3, and Convolutional CERENKOV3, for discriminating regulatory single nucleotide polymorphisms (rSNPs) from non-regulatory SNPs within non-coding genetic loci. The CERENKOV models are designed for recognizing rSNPs in the context of...
Forest species classifications are becoming increasingly automated as advances are made in machine learning. The algorithms used to identify tree species range from simple decision trees to intricate neural networks, and often excel in accurately delineating tree species. However, complex algorithms can have high input costs, including the cost of...
Long noncoding RNAs (lncRNAs) are RNA molecules that are at least 200 nucleotides long and do not encode proteins. lncRNAs have roles in gene regulation, chromatin epigenetics, and molecular scaffolding. In light of mounting evidence implicating species-specific noncoding RNAs and gene regulatory mechanisms in species adaptations, it is reasonable to...
While monocytes are vital for host defense against pathogens, in cases of non-resolving inflammation, monocytes and their differentiated progeny can secrete tissue-damaging factors, present auto-antigens, and promote the inflammatory response. In this study, a systems biology approach was used to map human monocyte gene regulatory regions by integrating expression quantitative...
While monocytes are vital for host defense against pathogens, in cases of non-resolving inflammation, monocytes and their differentiated progeny can secrete tissue-damaging factors, present auto-antigens, and promote the inflammatory response. In this study, a systems biology approach was used to map human monocyte gene regulatory regions by integrating expression quantitative...
Lodgepole pine (Pinus conorta) is a widely distributed forest type across western North America. Central Oregon lodgepole pine forests are ecologically unique when compared to other lodgepole pine ecosystems. Sierra lodgepole pine (Pinus contorta ssp. murrayana) is the dominant variety and often exists as the climax species on pumice soils,...
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StephenA. Fitzgerald
Lodgepole pine (Pinus conorta) is a widely distributed forest type
This thesis investigates the dynamic efficiency of emission standards and
Pigouvian taxes in the regulation of pollution where research and development (R&D)
and the technology level are endogenous. A key element of the analysis is a comparison
of the efficiency between instances in which the regulator can and cannot commnit...