Clostridium perfringens type A isolates, an anaerobic enterotoxigenic spore forming bacterium, are the third leading cause of food-borne disease in the United States. Factors that contribute to the virulence of C. perfringens include the ability of the bacterium to form heat resistant spores and to produce an enterotoxin (CPE). Although...
Cnidarians, such as anemones and corals, engage in an intracellular symbiosis with
photosynthetic dinoflagellates. Corals form both the trophic and structural foundation of
reef ecosystems. Despite their environmental importance, little is known about the
molecular basis of this symbiosis. In this dissertation we explored the cnidariandinoflagellate symbiosis from two perspectives:...
Mutations to superoxide dismutase were the first proven cause of Lou
Gehrig’s disease (amyotrophic lateral sclerosis; ALS) implicating superoxide in
the selective death of motor neurons that characterizes ALS. Nitric oxide
competes effectively with superoxide dismutase for superoxide to form the
powerful oxidant peroxynitrite. Endogenous formation of peroxynitrite can kill...
Oregon State University has recently conducted a complete core conversion analysis as part of the Reduced Enrichment for Research and Test Reactors Pprogram. The goals of the thermal hydraulic analyses were to calculate natural circulation flow rates, coolant temperatures and fuel temperatures as a function of core power for both...
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4.4: COMPARISON OF OSTR FUEL ROD AXIAL CHARACTERISTICS AND RELAP SUBCHANNEL...............34
Influences of operating conditions on the production of carbon nanotubes
(CNTs) were studied using Fe and Fe-Ni bimetallic catalysts supported on silicon
monoxide (SiO). The catalysts were prepared in three steps: (1) impregnation of SiO
powders with ferric nitride or combinations of ferric and nickel nitrides, (2) oxidation
of nitrides...
Patterning of metal oxides typically involves a multi step process, involving
depositing a resist, patterning that resist with some form of lithography, etching the
oxide through the resist, and finally removing. This process can be simplified if the
resist is removed and replaced with a metal oxide that can be...
EF-hand proteins are a conserved family of proteins that are modulated by divalent cations and regulate diverse cellular activities. In the present study we characterized the molecular determinants of myosin regulatory light chain (RLC) interaction with several subunits of the N-methyl-D-aspartate (NMDA)-type glutamate receptor. Myosin RLC is an EF-hand protein...
Vibrio parahaemolyticus is a seafood-borne pathogen that can cause gastroenteritis in humans. This study investigated the effectiveness of refrigerated seawater (5°C) depuration on reducing V. parahaemolyticus in raw Pacific oysters (Crassostrea gigas). Raw Pacific oysters were inoculated with a mixed culture of five clinical strains of V. parahaemolyticus and depurated...
This thesis describes the chemical investigation of marine cyanobacteria collected in Madagascar and Panama with an emphasis on the isolation and structure elucidation of medicinally relevant secondary metabolites.
A collection of the marine cyanobacterium Lyngbya majuscula from the Radames Islands, Madagascar yielded two new cyclic depsipeptides, radamamides A and B,...