Since 1939, scientists have studied estrous cycle manipulation in dogs resulting in more articles published in this field than any other area of canine reproduction. Estrous cycle manipulation in dogs must be safe and reliable. Dopamine agonists, gonadotropin-releasing hormone agonists, and gonadotropins are hormones that have been used for estrus...
Placental pathologies are not uncommon in dogs. For example, in primiparous bitches, the reported incidence of subinvolution of placental sites is 21% - 100%. Despite years of research in multiple species, the mechanisms regulating late gestation trophoblast behavior in the dog remain unexamined. Therefore, the objective of this study was...
Camelid health and parasitology experts disagree on what a “safe” level of internal parasitism is in camelids. The objective was to determine the levels of parasitism in show camelids (llamas and alpacas). The hypothesis was that fecal egg counts (FEC) in camelid would differ based upon geographic location, species (llama...
Sheep are seasonally polyestrus, which means they do exhibit estrus and ovulation during the short daylight (breeding season) and do not during the long daylight (nonbreeding season). To stimulate the ewes to ovulate during the nonbreeding season, various hormonal treatments have been used. PG-600 contains both equine chorionic gonadotropin and...
There are over two million pet rabbits in the United States. Many rabbits are obtained as adults from pet stores and humane societies. Pet rabbit owners may elect to perform ovariohysterectomy (spay) surgeries on female rabbits to prevent unwanted pregnancies as well as to eliminate the possibility of reproductive disorders...
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MichelleKutzler, Mentor, representing Department of Animal and Rangeland Sciences
Sperm acrosome associated 3 protein (SPACA3) is a unique, intra-acrosomal, conventional-type lysozyme-like protein of mammalian spermatozoa. SPACA3 is present in all stages of ovarian follicles and is localized to granulosa cells and ooplasma in humans, mice, cows, dogs, and cats. The objective of this study was to determine if equine...
Gonadectomy has been associated with a 1.5-2 fold increase in the occurrence of canine hip dysplasia and a 2-3 fold increase in the occurrence of canine anterior cruciate ligament (ACL) injury. In intact dogs, luteinizing hormone (LH) is secreted from the adenohypophysis to stimulate the synthesis of gonadal hormones, which...
Reproductive function in the dog is controlled by feedback mechanisms that involve the hypothalamus, the anterior pituitary gland, and the gonads. Surgical gonad removal, a common procedure performed in dogs for the purposes of sterilization, disrupts the hypothalamic-pituitary-gonadal (HPG) axis and results in permanently elevated concentrations of gonadotropins. Manipulation of...
Luteinizing hormone (LH) stimulates the secretion of gonadal steroid hormones (testosterone in males and estrogen/progesterone in females) and is under negative feedback from gonadal hormones. In gonad-intact dogs, LH is secreted in low amplitude pulses of concentrations under 1 ng/mL; except for the day of the LH surge in females...
This research investigated gene expression in the canine placenta during the peripartum period. Previous studies have recognized molecular changes that occur in the placenta around the time of placental release in other species, but no study has looked at gene expression in the late gestation canine placenta. Of particular significance...