Relational binary operators, such as join, are arguably the most costly and frequently used operations in relational data systems. In many join algorithms, the majority of the process time is spent on scanning and attempting to join the parts of the relations that do not satisfy the join condition and...
Animals aggregate and interact in nonuniform and nonrandom patterns, which lead to group level characteristics that have important evolutionary and ecological consequences. Network analysis provides a useful conceptual framework for linking animal interactions at all scales from dyads to communities, to populations and ecosystems. Despite exciting theoretical and applied advances...
Messenger RNA (mRNA) therapy has massive potential to treat various genetic disorders by providing effective proteins to the diseased cells and tissues. Its therapeutic applications include protein replacement, genome editing, and immunotherapy. For successful mRNA treatment, mRNA must be delivered to the cytosol of target cells. One of the leading...
Anthropogenic climate change is threatening biodiversity as I currently understand it. There is now a large body of work highlighting species responses, globally, to this threat. Importantly, responses at the species level emerge from responses at lower levels of biological organization (individuals and populations) across a species’ geographic range. For...
Multi-relation aggregation queries process the join operator before computing the aggregation function. This join is arguably the most costly operation since traditional join algorithms spend majority of their time trying to join the parts of the relations that do not generate any output tuples. This causes slow response times with...
At the intersection of basic science research and clinical relevance, cancer metastasis and cell invasion is a multifaceted problem that has been investigated for the past several decades. Importantly, cancer cell plasticity, the ability of a single cell to change its phenotype without genetic mutations in response to environmental cues,...
The development of nuclear fuel and materials requires is a continuous effort to investigate the acute and prolonged effects of irradiation, thermal-material stress, chemical change, or other conceivable damage mechanics acquired during normal operation or accident scenarios throughout its lifetime. As in-core fuel property measurement techniques advance to support in...
Disease detection through traditional techniques such as scouting fields on foot, molecular assays, or morphological identification of plant pathogens is time consuming and costly. Disease diagnosis in the field can be extremely subjective, and largely depends on the experience and knowledge of pathogen identification and disease quantification. This thesis provides...