A pro-inflammatory agent, lipopolysaccharide, can mimic the effects of aging on spatial reference memory
E. R. ESCOBEDO and K. R. Magnusson, Dept. of Biomedical Sciences, Coll. of Vet. Med., Linus Pauling Institute, Oregon State University, Corvallis, OR 97331
Humans and rodents experience declines in reference (long-term), working (short-term) memory, and...
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Memory
E. R. Escobedo1, K. Magnusson2,3 —1BioResource Research, 2Department of Biomedical Sciences
A pro-inflammatory agent, lipopolysaccharide, can mimic the effects of aging on spatial reference memory
E. R. ESCOBEDO and K. R. Magnusson, Dept. of Biomedical Sciences, Coll. of Vet. Med., Linus Pauling Institute, Oregon State University, Corvallis, OR 97331
Humans and rodents experience declines in reference (long-term), working (short-term) memory, and...
Full Text:
, Lipopolysaccharide, Can Mimic the Effects of Aging on Spatial Reference Memory
E. R. Escobedo1, K. Magnusson2,3
A pro-inflammatory agent, lipopolysaccharide, can mimic the effects of aging on spatial reference memory
E. R. ESCOBEDO and K. R. Magnusson, Dept. of Biomedical Sciences, Coll. of Vet. Med., Linus Pauling Institute, Oregon State University, Corvallis, OR 97331
Humans and rodents experience declines in reference (long-term), working (short-term) memory, and...
Western diets are high in fat and sucrose and can influence behavior and gut microbiota. There is growing evidence that altering the microbiome can influence the brain and behavior. This study was designed to determine whether diet-induced changes in the gut microbiota could contribute to alterations in anxiety, memory or...
The NMDA receptor is an important component of spatial working and reference memory. The receptor is a heterotetramer composed of a family of related subunits. The GluN2B subunit of the NMDA receptor appears to be essential for some forms of memory and is particularly vulnerable to change with age in...
According to the “social intelligence hypothesis,” species with complex social interactions have
more sophisticated communication systems. Giant otters (Pteronura brasiliensis) live in groups
with complex social interactions. It is likely that the vocal communication of giant otters is more
sophisticated than previous studies suggest. The objectives of the current study...
The GluN1 subunit of the NMDA receptor shows age-related changes in its
expression pattern, some of which correlate with spatial memory performance in mice.
Aged C57BL/6 mice show an age-related increase in mRNA expression of GluN1
subunit splice variants that lack the N terminal splice cassette, GluN1ₒₓₓ (GluN1-a). This
increase...
The protein palmitoylation cycle has been shown to be important for protein signaling and synaptic plasticity. Data from our lab showed a change in the palmitoylation status of certain proteins with age. A greater percentage of the NMDA receptor subunits GluN2A and GluN2B, along with Fyn and PSD95 proteins, were...
It is critical to study factors that are important for origin and maintenance of biological
diversity. A comparative approach involving a large number of populations is
particularly useful.We use this approach to study the relationship between ecological
factors and phenotypic diversity in Icelandic Arctic charr (Salvelinus alpinus).
Numerous populations of...