Surface sediment transport is an important geomorphic process which can be significantly altered by management activities in forested ecosystems. Disturbance of the soil surface may result in increased sediment delivery to fish bearing streams and degradation of soil structure. Selective thinning and low impact yarding techniques were utilized in an...
Affecting an estimated 1.7 million people annually, traumatic brain injury has been labeled a major public health threat. As the leading cause of death and disability in young people, and the signature wound of the wars in Iraq and Afghanistan, the issue is drawing increased media attention. Analyses begin by...
Water fluoridation is considered one of the top ten greatest health achievements of the twentieth century due to its effectiveness in reducing the prevalence of dental caries. However, despite extensive research on the subject, there is little information currently available about how the constituents of drinking water affect the uptake...
Mangroves provide numerous ecosystem services, including biodiversity values such as nesting sites for piscivorous waterbirds. High concentrations of pisicivoirous birds are hypothesized to affect ecosystem dynamics, yet few studies have examined their effects in mangroves. We examined the effects of nutrient enrichment by colonial waterbirds at a mangrove rookery in...
Childhood tooth decay is a prevalent and concerning public health issue that is often misunderstood or dismissed. In Oregon specifically, over 50% of children have experienced at least one instance of tooth decay and these rates are even higher for marginalized communities such as children living in poverty, children of...
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Philip McFadden
Childhood tooth decay is a prevalent and concerning public health issue that is
Blood vessel injury was found to release intracellular pools of protein
D-aspartyl/L-isoaspartyl carboxyl methyltransferase (PIMT) into the extracellular
milieu, where it became trapped. Trapped PIMT was able to utilize radiolabeled
S-adenosyl-L-methionine (AdoMet) introduced into the circulation to methylate
blood vessel proteins containing altered aspartyl residues specifically at the site
of...
Methodologies that detect biologically active substances have important potential applications for medical diagnostics, drug discovery, and chemical and biological anti-terrorism efforts. The wide spectrum of potential analytes that induce a physiological response dictates that novel techniques be developed to more rapidly screen and characterize agents that are more economical and...
This thesis explores the feasibility of using melanophore-based biosensors from Oreochromis niloticus. Melanophores are one type of pigmented cell of the scales and fins of fish that respond in a motile fashion to a diverse range of stimuli. Fish scales were employed as the first step in determining the utility...
Every cell is faced continuously with the task of transducing a vast number of external signals into appropriate intracellular responses. In mammalian cells, membrane bound receptors modulate the production of secondary messenger molecules, such as cyclic AMP (cAMP). Cell signaling through second messengers relies on the diffusion of such second...