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  • Bang-bang control development of permeability changes in a membrane model

    Creator:
    Melendy, Robert F.
    Abstract:
    The application of systems and control theory to membrane physiology is presented here. Modeling efforts have focused on describing those physiologically realistic mechanisms which govern the regulation of membrane permeability in nerve. The motivation behind identifying such mechanisms lies in understanding the morphology of neural activity on a meaningful and...
    Resource Type:
    Masters Thesis

  • Structural effects of intrinsic and extrinsic perturbations to model membranes

    Creator:
    Church, Sara E.
    Abstract:
    The observed and calculated structural parameters of three systems of phosphatidylcholine bilayers in fully-hydrated multilamellar vesicles (MLVs) were determined using x-ray diffraction techniques. The analysis used the x-ray reflections from the low-, intermediateand wide-angle regions of the diffraction patterns in the subgel, gel, rippled and fluid phases to determine the...
    Resource Type:
    Dissertation
    Full Text:
    , such as permeability, compressibility and ability to partition solutes [2,9- 11,14,30-31]. Membrane

  • Functional and Structural Analyses of Three Distinct proteins by Biochemical and Biophysical Techniques

    Creator:
    Codding, Sara Jone
    Abstract:
    The focus of this dissertation was to understand protein function and structure ona molecular level. To do this successfully, a variety of biochemical and biophysicaltechniques were employed. A wide variety of techniques were applied to study theproteins of interest in this dissertation to probe protein-protein interactions, proteinfunction, protein structure, and...
    Resource Type:
    Dissertation
    Full Text:
    resealing the cell membrane upon routine injury. We demonstrate that dysferlin catalyzes the rate-limiting