Studies towards the total synthesis of (−)-kendomycin (1), a bacterial metabolite with
a unique molecular architecture and pronounced biological activity, are described. These
studies resulted in the synthesis of advanced intermediate 208, containing all of the
carbon atoms of 1.
A Dötz annulation between alkyne 122 and novel chromium carbenoid...
3D datasets acquire great importance in the context of medical imaging. In this thesis we survey and enhance solutions to problems inherently associated with 3D datasets-processing time,noise and visualization. Efforts include development of a tool kit to provide a multi-threaded processing platform to cut processing time, produce real time visualization...
The development of new technologies in science is a balance between existence and use. There are three versions of this duality – something is built and users come, something is built and users don’t come, and, finally, potential users show up but the ballpark has not yet been built. In...
Field studies indicate that accumulation of finely divided organic
debris in the channels of mountain streams after clearcutting may be
responsible for subsequent reduction in the dissolved oxygen concentration.
The purpose of this study was to quantify the biochemical
oxygen demand (BOD) of Douglas-fir needles and twigs, western
hemlock needles...
Motion capture data is a digital representation of the complex temporal structure of human motion. Motion capture is widely used for data-driven animation in sports,medicine and entertainment, because of its ability to capture complex and realistic
motions. Due to its efficiency and cost, methods for reusing collections of motion capture...
General purpose computer systems have seen increased performance potential through the parallel processing capabilities of multicore processors. Yet this potential performance can only be attained through parallel applications, thus forcing software developers to rethink how everyday applications are designed. The most readily form of Thread Level Parallelism (TLP) within any...
In the field of Human-Computer Interaction, provenance refers to the complete history and genealogy of a document. Provenance can be useful in identifying related resources, such as different versions of the same document or resources used in the creation of a new document. Though methods of provenance collection and applications...
Analysis, visualization, and design of vector fields on surfaces have a wide variety of major applications in both scientific visualization and computer graphics. On the one hand, analysis and visualization of vector fields provide critical insights to the flow data produced from simulation or experiments of various engineering processes. On...
While there are many ways to evaluate a user interface design, the user's mental workload and situation awareness (SA) are particularly important considerations in the supervisory control of safety-critical systems. Typically, operators of these systems must monitor high-volume, time-sensitive status information. Interface design for this domain can be challenging and...
The present increasing need for the development of empirical hypotheses that explain the decisionmakers' behavior towards risk is to provide an understanding of the framework within which an industry operates. Such hypotheses could facilitate the implementation of policies designed to solve problems identified within an industry and could also provide...