Index Catalog // ScholarsArchive@OSU

Hydrocortisone permeation study using a synthetic membrane, mouse skin and an epiderm cultured skin, Preparation of orally disintegrating tablets of melatonin and acetaminophen, Pharmacokinetics of terbinafine in penguins

Creator:: Le, Hang Thi
Abstract:: The first project of this thesis is an in vitro study. This study was performed with 8 hydrocortisone topical products on the market for the purpose of comparing one Tec Lab product, a Corticool gel, to the other seven common products on the market. The permeation of these products was...
Resource Type:: Dissertation
Full Text:: ) Preparation of Orally Disintegrating Tablet of Melatonin and Acetaminophen, (3) Pharmacokinetics of

Development and testing of a sustained release acetaminophen tablet for the treatment of chronic pain in osteoarthritis patients

Creator:: Keller, Carol Ann
Abstract:: Acetaminophen has been safely used for analgesia for many years. Literature suggests that a plasma acetaminophen level of 5μg/ml is necessary to maintain analgesic relief in humans. Current dosing regiments are inconvenient (every 4-6 hours) and do not maintain this minimum plasma level. Simulations were conducted to examine various doses...
Resource Type:: Dissertation
Full Text:: : Development and Testing of a Sustained Release Acetaminophen Tablet for the Treatment of Chronic Pain in

Evaluation of gastrointestinal transit time and novel oral acetaminophen product formulation

Creator:: Hossain, Mohammad
Abstract:: Gastrointestinal (GI) transit data were collected using pigs as animal models. Density and size effects of non-disintegrating dosage forms on GI transit were investigated. Total GI transit times range from 2 to 33 days for 22 administrations of these nondisintegrating dosage forms. Pigs are found to not be an appropriate...
Resource Type:: Dissertation
Full Text:: -disintegrating tablets of 3-7 mm diameter and pellets of 0.7-1.7 mm diameter emptied from the stomach of people

Formulation and pharmacokinetics of melatonin

Creator:: Konsil, Julraht
Resource Type:: Dissertation
Full Text:: INTRODUCTION 1 CHAPTER 1: Phannacokinetics And Dose Proportionality Of Melatonin Orally Given At High And Low

Pharmacokinetic modeling and simulations of gastrointestinal transit effects on drug pharmacokinetics from enteric-coated pellet formulations and their applications

Creator:: Watanalumlerd, Prapoch
Abstract:: Effects of gastrointestinal transit on plasma concentrations of drugs from enteric-coated pellet formulations were demonstrated using pharmacokinetic models describing plasma concentrations of drugs from various enteric-coated pellet formulations. Gastric emptying time, lag time of emptying, and drug release rate from pellets in the small intestine, along with other pharmacokinetic parameters...
Resource Type:: Dissertation
Full Text:: administration of immediate-release tablet and enteric-coated tablet (two different tablets in a capsule

A novel self-sealing chewable sustained release tablet of acetaminophen ; Development and evaluation of novel itraconazole oral formulations ; A novel zero order release matrix tablet

Creator:: Rakkanka, Vipaporn
Abstract:: This thesis describes evaluation of a novel self-sealing chewable sustained release tablet that can maintain controlled release of drug regardless of compaction, crushing, or chewing. The new formulation contains polyethylene oxide which produces a sealant effect for cracks produced in the polymer coating during compaction. Dissolution studies were conducted and...
Resource Type:: Dissertation
Full Text:: Chewable Sustained Release Tablet of Acetaminophen, (2) Development and Evaluation of Novel Itraconazole

New product formulations and pharmacokinetics of acetaminophen

Creator:: Borin, Marie T.
Resource Type:: Dissertation
Full Text:: acetaminophen powder. In vitro dissolution of intact ( and crushed (---) tablets containing spray-coated

In vitro and in vivo testing of a gastric retention device : development and evaluation of a new colonic delivery system

Creator:: Ahmed, Iman Saad
Abstract:: This thesis describes evaluation of a gastric retention device (GRD) developed at Oregon State University. The device was originally fabricated from Xanthan gum and Locust bean gum. A modified gastric retention device containing other additives was developed and investigated in this work. The modified device was evaluated in vitro for...
Resource Type:: Dissertation
Full Text:: made of acetaminophen loaded beads produced by extrusion and spheronization and coated with different

Development and in vivo testing of a gastric retention device (GRD) in dogs

Creator:: Kapsi, Shivakumar G.
Abstract:: This thesis describes 1) development of a gastric retention device (GRD) to increase gastric retention time of certain drugs, 2) product formulations of an immediate release itraconazole and controlled-release ketoprofen. GRD was fabricated from crosslinked carbohydrate polymers. Rate and extent of hydration of the film in water and in simulated...
Resource Type:: Dissertation
Full Text:: of Doctor of Philosophy in Pharmacy presented on November 24 1998. Title: 1) Development and In Vivo

Fish oral antigen delivery system development and optimization

Creator:: Zhang, Jia Ai (Allen)
Abstract:: Oral administration is the most practical way of vaccination of fish. It has advantages over intraperitoneal injection and immersion methods that include no stressful handling, no interference with routine fish husbandry and antigens can be delivered to the fish in their feed. An oral antigen delivery system was developed for...
Resource Type:: Dissertation
Full Text:: way of vaccination of fish. It has advantages over intraperitoneal injection and immersion methods

ScholarsArchive@OSU

Hydrocortisone permeation study using a synthetic membrane, mouse skin and an epiderm cultured skin, Preparation of orally disintegrating tablets of melatonin and acetaminophen, Pharmacokinetics of terbinafine in penguins

Development and testing of a sustained release acetaminophen tablet for the treatment of chronic pain in osteoarthritis patients

Evaluation of gastrointestinal transit time and novel oral acetaminophen product formulation

Formulation and pharmacokinetics of melatonin

Pharmacokinetic modeling and simulations of gastrointestinal transit effects on drug pharmacokinetics from enteric-coated pellet formulations and their applications

A novel self-sealing chewable sustained release tablet of acetaminophen ; Development and evaluation of novel itraconazole oral formulations ; A novel zero order release matrix tablet

New product formulations and pharmacokinetics of acetaminophen

In vitro and in vivo testing of a gastric retention device : development and evaluation of a new colonic delivery system

Development and in vivo testing of a gastric retention device (GRD) in dogs

Fish oral antigen delivery system development and optimization

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