Pseudomonas aeruginosa is an environmental bacterium which
opportunistically infects humans. Commonly residing in irondepleted
environments, P. aeruginosa uses iron-chelating
molecules called siderophores to scavenge iron from its
environment. The most prevalent siderophore used by P.
aeruginosa is known as pyoverdine. After the cell synthesizes and
secretes pyoverdine, the molecule binds...
Many bacteria possess cell density-dependent quorum-sensing (QS) systems that often regulate cooperative secretions involved
in host-microbe or microbe-microbe interactions. These secretions, or “public goods,” are frequently coregulated by stress and
starvation responses. Here we provide a physiological rationale for such regulatory complexity in the opportunistic pathogen
Pseudomonas aeruginosa. Using minimal-medium...
Full Text:
Mellbye and MartinSchuster#
Department of Microbiology and Molecular & Cellular Biology Program
Background: Acyl-homoserine lactone (acyl-HSL) and alkyl quinolone (AQ) based quorum-sensing (QS) systems are important for Pseudomonas aeruginosa virulence and biofilm formation. The effect of QS on biofilm formation is influenced by various genetic and environmental factors. Here, we used a colony biofilm assay to study the effect of the central...
Many bacteria possess cell density-dependent quorum-sensing (QS) systems that often regulate cooperative secretions involved
in host-microbe or microbe-microbe interactions. These secretions, or “public goods,” are frequently coregulated by stress and
starvation responses. Here we provide a physiological rationale for such regulatory complexity in the opportunistic pathogen
Pseudomonas aeruginosa. Using minimal-medium...
Full Text:
Goods in Pseudomonas aeruginosa
Brett Mellbye, MartinSchuster
Department of Microbiology and
Autoinduction (AI), the response to self-produced chemical signals,
is widespread in the bacterial world. This process controls
vastly different target functions, such as luminescence, nutrient
acquisition, and biofilm formation, in different ways and integrates
additional environmental and physiological cues. This diversity
raises questions about unifying principles that underlie all
AI...
Many bacteria possess cell density-dependent quorum-sensing (QS) systems that often regulate cooperative secretions involved
in host-microbe or microbe-microbe interactions. These secretions, or “public goods,” are frequently coregulated by stress and
starvation responses. Here we provide a physiological rationale for such regulatory complexity in the opportunistic pathogen
Pseudomonas aeruginosa. Using minimal-medium...
Published March 1934. Facts and recommendations in this publication may no longer be valid. Please look for up-to-date information in the OSU Extension Catalog: http://extension.oregonstate.edu/catalog
Published June 1940. Facts and recommendations in this publication may no longer be valid. Please look for up-to-date information in the OSU Extension Catalog: http://extension.oregonstate.edu/catalog
Published May 1929. Facts and recommendations in this publication may no longer be valid. Please look for up-to-date information in the OSU Extension Catalog: http://extension.oregonstate.edu/catalog
Published June 1941. Facts and recommendations in this publication may no longer be valid. Please look for up-to-date information in the OSU Extension Catalog: http://extension.oregonstate.edu/catalog